Evaluation of the effectiveness of platelet-rich plasma in the bone consolidation of patients submitted to lumbar arthrodesis.

Autor:	Rezende CF; Escola Superior de Ciências da Santa Casa de Misericórdia (Emescam), Vitória, ES, Brazil., Azevedo DP; Escola Superior de Ciências da Santa Casa de Misericórdia (Emescam), Vitória, ES, Brazil., Lourenço RB; Centro de Diagnóstico por Imagem (CDI) do Espírito Santo, Vitória, ES, Brazil., Duarte JF; Universidade Federal do Espírito Santo (UFES), Departamento de Ortopedia e Traumatologia, Vitória, ES, Brazil., Cardoso IM; Hospital Santa Casa de Misericórdia de Vitória, Grupo de Coluna Vertebral, Vitória, ES, Brazil., Jacob Júnior C; Hospital Santa Casa de Misericórdia de Vitória, Grupo de Coluna Vertebral, Vitória, ES, Brazil.
Jazyk:	angličtina
Zdroj:	Revista brasileira de ortopedia [Rev Bras Ortop] 2017 Oct 19; Vol. 52 (6), pp. 693-698. Date of Electronic Publication: 2017 Oct 19 (Print Publication: 2017).
DOI:	10.1016/j.rboe.2017.10.006
Abstrakt:	Objective: To determine whether the use of autograft associated with platelet-rich plasma (PRP) increases bone healing in patients undergoing lumbar fusion. Method: This was a prospective, descriptive, and comparative study, which included 40 patients undergoing lumbar fusion, who were divided into two groups: group I, autograft only, and group II, autograft associated with PRP. After surgery, patients were followed-up on the first, third, and sixth month. The Molinari radiographic classification and Glassman tomographic classification were used as criteria to analyze the bone consolidation. Result: Comparing the group I with group II, according to the criteria of Molinari, bilateral fusion was observed in 27.5% of the patients in group I in the first month after surgery. In group II, the rate of bilateral fusion was 25.0% and 20% in the third and sixth months, respectively. The results of computed tomography scans performed at six months after surgery indicated, according to the criteria of Glassman, a rate of bilateral solid fusion of 15.0% and 10.0% in groups I and II, respectively. Conclusion: The use of PRP showed no significant difference in bone healing in cases of lumbar arthrodesis.
Databáze:	MEDLINE
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