Collision skin lesions-results of a multicenter study of the International Dermoscopy Society (IDS).

Autor:	Blum A; Public, Private and Teaching Practice of Dermatology, Konstanz, Germany., Siggs G; SunDoctors Skin Cancer Clinic, Glenunga, Adelaide, Australia., Marghoob AA; Department of Dermatology, Memorial Sloan Kettering Skin Cancer Center, New York, NY, USA., Kreusch J; Public and Private Practice of Dermatology, Lübeck, Germany., Cabo H; Research Institut, University of Buenos Aires, Argentina., Campos-do-Carmo G; Gávea Medical Center, Rio de Janeiro, Brazil., Shiraishi AFC; Dermatology Service, Hospital e Maternidade Celso Pierro, PUCC, Campinas, Sao Paulo, Brazil., Kienitz A; Public and Private Practice of Dermatology, Dingolfing, Germany., Maldonado-Seral C; Department of Dermatology, Hospital Universitario Central de Asturias, Oviedo, Spain., Maltagliati-Holzner P; Public and Private Practice of Dermatology, Stuttgart, Germany., Mijuskovic ZP; Department of Dermatology and Venereology, Faculty of Medicine, Military Medical Academy, Belgrade, Serbia., Yoshimura AM; University of Campinas, Campinas, Brazil., Moscarella E; Dermatology and Skin Cancer Unit, Arcispedale S. Maria Nuova, IRCCS, Reggio Emilia, Italy., Rabinovitz HS; University of Miami, Miller School of Medicine, Miami, FL, USA., Rodriguez-Garcia C; Department of Dermatology, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain., Saa SR; Department of Dermatology, Hospital Del Carmen, Mendoza, Argentina., Rubegni P; Department of Clinical Medicine and Immunological Science, Dermatology Section, University of Siena, Siena, Italy., Savoia F; Unit of Dermatology, AUSL della Romagna, Lugo, Italy., Simionescu O; 1st Clinic of Dermatology, Carol Davila University of Medicine and Pharmacy, Colentina Hospital, Bucharest, Romania., Diego PZ; Dermatology Department, Hospital de Sant Pau i Santa Tecla, Tarragona, Spain., Hofmann-Wellenhof R; Department of Dermatology, Medical University of Graz, Graz, Austria.
Jazyk:	angličtina
Zdroj:	Dermatology practical & conceptual [Dermatol Pract Concept] 2017 Jul 31; Vol. 7 (4), pp. 51-62. Date of Electronic Publication: 2017 Jul 31 (Print Publication: 2017).
DOI:	10.5826/dpc.0704a12
Abstrakt:	Background: Collision lesions as two independent and unrelated skin tumors often manifest an atypical morphology. Objective: To determine the combinations of collision skin lesions (CSLs). Methods: Twenty-one pigmented lesion clinics in nine countries included 77 histopathologically proven CSLs in this retrospective observational study. Results: Seventy-seven CSLs from 75 patients (median age 59.8 years) were analyzed; 24.7% of CSLs were located on the head and neck area, 5.2% on the upper extremities, 48.1% on the trunk, and 11.7% on the lower extremities; 40.3% revealed a melanocytic component (median age 54.7 years), followed by 45.5% with a basal cell carcinoma (BCC) (median age 62.4 years) and 11.7% with a seborrheic keratosis (median age 64.7 years). CSLs with a BCC component were more often found on the head and neck area compared to tumors with a melanocytic component (34.3% versus 16.1%). Lesions with a melanocytic component were more often detected on the trunk compared to lesions with a BCC (64.5% versus 37.1%). Patients with CSLs with epidermal-epidermal cell combination were older than patients with epidermal-dermal cell combination (63 versus 55.2 years), were more often male than female (63% versus 43.3%), more often had the lesion on the head and neck area (32.6% versus 13.3%), and less often on the upper (2.2 % versus 10%) or lower extremities (8.7% versus 16.6%). Conclusions: CSLs consist of a heterogeneous group of lesions of varying cell types. They are associated with advancing age and cumulative UV-exposure. CSLs manifest a complex morphology making it challenging to diagnose correctly. Competing Interests: Competing interests: The authors have no conflicts of interest to disclose.
Databáze:	MEDLINE
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