Hepatitis E: A Literature Review.

Autor: Guerra JAAA; Nossa Senhora das Graças Hospital, Alcides Munhoz Street, 433 - Mercês, Curitiba - PR, Brazil., Kampa KC; Nossa Senhora das Graças Hospital, Alcides Munhoz Street, 433 - Mercês, Curitiba - PR, Brazil., Morsoletto DGB; Nossa Senhora das Graças Hospital, Alcides Munhoz Street, 433 - Mercês, Curitiba - PR, Brazil., Junior AP; Nossa Senhora das Graças Hospital, Alcides Munhoz Street, 433 - Mercês, Curitiba - PR, Brazil., Ivantes CAP; Nossa Senhora das Graças Hospital, Alcides Munhoz Street, 433 - Mercês, Curitiba - PR, Brazil.
Jazyk: angličtina
Zdroj: Journal of clinical and translational hepatology [J Clin Transl Hepatol] 2017 Dec 28; Vol. 5 (4), pp. 376-383. Date of Electronic Publication: 2017 Aug 18.
DOI: 10.14218/JCTH.2017.00012
Abstrakt: Hepatitis E is the fifth known form of human viral hepatitis. Although not very common in our clinical practice, the incidence in Western countries is increasing. Infection with the hepatitis E virus (HEV) may be related to acute illness, liver failure, chronic hepatitis and cirrhosis. HEV itself is an RNA virus, with eight described genotypes (HEV 1-8), four of which more commonly affect humans and have, thus, been better studied. Besides liver manifestations, genotype 3 is also related to extra-hepatic manifestations, such as neurological, renal and rheumatological. Evolution to chronic disease occurs especially in patients who underwent transplantation, have hematological malignancies requiring chemotherapy, or have infection with the human immunodeficiency virus. The diagnosis may be difficult because of the low availability of tests and due to low sensibility and specificity. The acute form of illness does not have to be treated, but the chronic one does. We present here a literature review of hepatitis E and the relation between chronic hepatitis E and transplantation.
Competing Interests: The authors have no conflict of interests related to this publication.
Databáze: MEDLINE
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