Development of forced normalisation psychosis with ethosuximide.
| Autor: | Apap Mangion S; Department of Telemetry, University College London, Institute of Neurology, London, UK., Rugg-Gunn F; Deparment of Neurology, National Hospital for Neurology and Neurosurgery, London, UK. |
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| Jazyk: | angličtina |
| Zdroj: | BMJ case reports [BMJ Case Rep] 2017 Dec 07; Vol. 2017. Date of Electronic Publication: 2017 Dec 07. |
| DOI: | 10.1136/bcr-2017-220838 |
| Abstrakt: | A 50-year-old man with known multidrug resistant coexistent focal and generalised epilepsy was commenced on ethosuximide, with normalisation of his electroencephalogram and cessation of absence seizures. Within 3 weeks, he developed a rapidly worsening paranoid psychosis with visual and olfactory hallucinations. A month after the cessation of ethosuximide and concurrent treatment with olanzapine, his psychosis resolved and permitted reinitiation of ethosuximide at a lower dose without recurrence of psychotic symptoms. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.) |
| Databáze: | MEDLINE |
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