Synthesis of N,S-Heterocycles and Dithiocarbamates by the Reaction of Dithiocarbamic Acids and S-Alkyl Dithiocarbamates with Nitroepoxides.

Autor: Ziyaei Halimehjani A; Faculty of Chemistry, Kharazmi University , 49 Mofateh Street, Tehran 15719-14911, Iran., Lotfi Nosood Y; Faculty of Chemistry, Kharazmi University , 49 Mofateh Street, Tehran 15719-14911, Iran.
Jazyk: angličtina
Zdroj: Organic letters [Org Lett] 2017 Dec 15; Vol. 19 (24), pp. 6748-6751. Date of Electronic Publication: 2017 Dec 06.
DOI: 10.1021/acs.orglett.7b03501
Abstrakt: A facile and efficient procedure for the synthesis of substituted thiazole-2(3H)-thiones and thiazolidine-2-thiones by the reaction of primary amines, carbon disulfide, and nitroepoxides is described. By using secondary amines in this protocol, the corresponding dithiocarbamate-substituted phenyl-2-propanones were prepared in excellent yields. In addition, substituted thiazoles and 1-(alkylthio)-1-phenylpropan-2-ones were prepared in reactions of S-alkyl dithiocarbamates and nitroepoxides.
Databáze: MEDLINE