| Autor: |
Wulff J; Department of Pediatrics, Baylor College of Medicine.; Texas Children's Cancer and Hematology Centers., Margolin J; Department of Pediatrics, Baylor College of Medicine.; Texas Children's Cancer and Hematology Centers., Coleman NE; Department of Pediatrics, Baylor College of Medicine.; Section of Critical Care Medicine., Demmler-Harrison G; Department of Pediatrics, Baylor College of Medicine.; Section of Infectious Diseases, Houston, TX., Lam F; Department of Pediatrics, Baylor College of Medicine.; Section of Critical Care Medicine., Shah MD; Department of Pediatrics, Baylor College of Medicine.; Texas Children's Cancer and Hematology Centers. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2018 Apr; Vol. 40 (3), pp. e185-e190. |
| DOI: |
10.1097/MPH.0000000000001024 |
| Abstrakt: |
We discuss a child with severe thrombocytopenia and mild anemia admitted to the Hematology service who quickly deteriorated to a life-threatening state. However, once rickettsial disease was considered in the differential diagnosis and empiric doxycycline begun, she quickly and fully recovered. A diagnostic panel, including Rickettsia typhi serology, confirmed the diagnosis of murine typhus but this occurred weeks after she had recovered. Given the potential severity of rickettsial diseases and the ease of modern travel across geographic borders, hematology-oncology providers everywhere must consider rickettsial diseases in their differential diagnosis of critically ill children and begin empiric therapy with doxycycline promptly. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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