Progress towards a vaccine against Ebola to meet emergency medical countermeasure needs.

Autor: Wolfe DN; Health and Human Services (HHS)/Assistant Secretary for Preparedness and Response (ASPR)/Biomedical Advanced Research and Development Authority (BARDA), Thomas P. O'Neill Federal Building (FOB8), 200 C Street, SW, Washington, DC 20024, United States. Electronic address: daniel.wolfe2@hhs.gov., Zarrabian AG; Health and Human Services (HHS)/Assistant Secretary for Preparedness and Response (ASPR)/Biomedical Advanced Research and Development Authority (BARDA), Thomas P. O'Neill Federal Building (FOB8), 200 C Street, SW, Washington, DC 20024, United States., Disbrow GL; Health and Human Services (HHS)/Assistant Secretary for Preparedness and Response (ASPR)/Biomedical Advanced Research and Development Authority (BARDA), Thomas P. O'Neill Federal Building (FOB8), 200 C Street, SW, Washington, DC 20024, United States., Espeland EM; Health and Human Services (HHS)/Assistant Secretary for Preparedness and Response (ASPR)/Biomedical Advanced Research and Development Authority (BARDA), Thomas P. O'Neill Federal Building (FOB8), 200 C Street, SW, Washington, DC 20024, United States.
Jazyk: angličtina
Zdroj: Vaccine [Vaccine] 2019 Nov 15; Vol. 37 (48), pp. 7178-7182. Date of Electronic Publication: 2017 Dec 02.
DOI: 10.1016/j.vaccine.2017.10.111
Abstrakt: The Ebola virus epidemic in West Africa proved to be the largest in the history of filovirus outbreaks, causing the World Health Organization to declare a public health emergency of international concern in August of 2014. In collaboration with domestic and international partners, the Biomedical Advanced Research and Development Authority (BARDA) initiated several vaccine development projects in support of the overall response efforts. The urgency associated with the epidemic triggered the clinical evaluation of lead vaccine candidates starting in late 2014. Here we will discuss development of the lead vaccine candidates for Ebola virus, specifically Zaire ebolavirus.
(Published by Elsevier Ltd.)
Databáze: MEDLINE
Externí odkaz: