Influence of the electrolyte's pH on the properties of electrochemically deposited hydroxyapatite coating on additively manufactured Ti64 alloy.

Autor: Vladescu A; National Institute for Optoelectronics, Department for Advanced Surface Processing and Analysis by Vacuum Technologies, 409 Atomistilor St., Magurele, RO77125, Romania.; National Research Tomsk Polytechnic University, Lenin Avenue 43, Tomsk, 634050, Russia., Vranceanu DM; University Politehnica of Bucharest, 313 Spl. Independentei, Bucharest, RO60042, Romania., Kulesza S; Warmia and Mazury University in Olsztyn, Department of Mathematics and Computer Science, Słoneczna 54, Olsztyn, 10-719, Poland., Ivanov AN; Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery of Federal State Budgetary Educational Institution of Higher Education 'V.I. Razumovsky Saratov State Medical University' of the Ministry of Healthcare of the Russian Federation, 148 Chernyshevskogo st., Saratov, 410012, Russia., Bramowicz M; Warmia and Mazury University in Olsztyn, Department of Mathematics and Computer Science, Słoneczna 54, Olsztyn, 10-719, Poland., Fedonnikov AS; Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery of Federal State Budgetary Educational Institution of Higher Education 'V.I. Razumovsky Saratov State Medical University' of the Ministry of Healthcare of the Russian Federation, 148 Chernyshevskogo st., Saratov, 410012, Russia., Braic M; National Institute for Optoelectronics, Department for Advanced Surface Processing and Analysis by Vacuum Technologies, 409 Atomistilor St., Magurele, RO77125, Romania., Norkin IA; Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery of Federal State Budgetary Educational Institution of Higher Education 'V.I. Razumovsky Saratov State Medical University' of the Ministry of Healthcare of the Russian Federation, 148 Chernyshevskogo st., Saratov, 410012, Russia., Koptyug A; Additive Manufacturing Group, Sports Tech Research Centre, Mid Sweden University, Akademigatan 1, Östersund, 831 25, Sweden., Kurtukova MO; Department of Histology, Federal State Budgetary Educational Institution of Higher Education 'V.I. Razumovsky Saratov State Medical University' of the Ministry of Healthcare of the Russian Federation, 112 Bolshaya Kazachia st., Saratov, 410012, Russia., Dinu M; National Institute for Optoelectronics, Department for Advanced Surface Processing and Analysis by Vacuum Technologies, 409 Atomistilor St., Magurele, RO77125, Romania., Pana I; National Institute for Optoelectronics, Department for Advanced Surface Processing and Analysis by Vacuum Technologies, 409 Atomistilor St., Magurele, RO77125, Romania., Surmeneva MA; National Research Tomsk Polytechnic University, Lenin Avenue 43, Tomsk, 634050, Russia., Surmenev RA; National Research Tomsk Polytechnic University, Lenin Avenue 43, Tomsk, 634050, Russia., Cotrut CM; University Politehnica of Bucharest, 313 Spl. Independentei, Bucharest, RO60042, Romania. cosmin.cotrut@upb.ro.; National Research Tomsk Polytechnic University, Lenin Avenue 43, Tomsk, 634050, Russia. cosmin.cotrut@upb.ro.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2017 Dec 01; Vol. 7 (1), pp. 16819. Date of Electronic Publication: 2017 Dec 01.
DOI: 10.1038/s41598-017-16985-z
Abstrakt: Properties of the hydroxyapatite obtained by electrochemical assisted deposition (ED) are dependent on several factors including deposition temperature, electrolyte pH and concentrations, applied potential. All of these factors directly influence the morphology, stoichiometry, crystallinity, electrochemical behaviour, and particularly the coating thickness. Coating structure together with surface micro- and nano-scale topography significantly influence early stages of the implant bio-integration. The aim of this study is to analyse the effect of pH modification on the morphology, corrosion behaviour and in vitro bioactivity and in vivo biocompatibility of hydroxyapatite prepared by ED on the additively manufactured Ti64 samples. The coatings prepared in the electrolytes with pH = 6 have predominantly needle like morphology with the dimensions in the nanometric scale (~30 nm). Samples coated at pH = 6 demonstrated higher protection efficiency against the corrosive attack as compared to the ones coated at pH = 5 (~93% against 89%). The in vitro bioactivity results indicated that both coatings have a greater capacity of biomineralization, compared to the uncoated Ti64. Somehow, the coating deposited at pH = 6 exhibited good corrosion behaviour and high biomineralization ability. In vivo subcutaneous implantation of the coated samples into the white rats for up to 21 days with following histological studies showed no serious inflammatory process.
Databáze: MEDLINE
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