Aryl hydrocarbon receptor overexpression in miniaturized follicles in female pattern hair loss.

Autor: Ramos PM; Department of Dermatology and Radiotherapy - Faculdade de Medicina de Botucatu - Universidade Estadual Paulista 'Júlio de Mesquita Filho' (FMB-UNESP) - Botucatu (SP), Brazil., Brianezi G; Department of Pathology - Faculdade de Medicina de Botucatu - Universidade Estadual Paulista 'Júlio de Mesquita Filho' (FMB-UNESP) - Botucatu (SP), Brazil., Martins ACP; Department of Pathology - Faculdade de Medicina de Botucatu - Universidade Estadual Paulista 'Júlio de Mesquita Filho' (FMB-UNESP) - Botucatu (SP), Brazil., Silva MGD; Department of Pathology - Faculdade de Medicina de Botucatu - Universidade Estadual Paulista 'Júlio de Mesquita Filho' (FMB-UNESP) - Botucatu (SP), Brazil., Marques MEA; Department of Pathology - Faculdade de Medicina de Botucatu - Universidade Estadual Paulista 'Júlio de Mesquita Filho' (FMB-UNESP) - Botucatu (SP), Brazil., Miot HA; Department of Dermatology and Radiotherapy - Faculdade de Medicina de Botucatu - Universidade Estadual Paulista 'Júlio de Mesquita Filho' (FMB-UNESP) - Botucatu (SP), Brazil.
Jazyk: angličtina
Zdroj: Anais brasileiros de dermatologia [An Bras Dermatol] 2017 May-Jun; Vol. 92 (3), pp. 430-431.
DOI: 10.1590/abd1806-4841.20175150
Abstrakt: The etiopathogenesis of female pattern hair loss is still poorly understood. In addition to genetic and hormonal elements, environmental factors could be involved. The aryl hydrocarbon receptor is expressed in keratinocytes and can be activated by environmental pollutants leading to alterations in the cell cycle, inflammation, and apoptosis. Here we demonstrate the overexpression of nuclear aryl hydrocarbon receptors in miniaturized hair follicles in female pattern hair loss.
Databáze: MEDLINE