Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations.

Autor: Rennert RC; Department of Neurosurgery, University of California, San Diego; rrennert@ucsd.edu., Steinberg JA; Department of Neurosurgery, University of California, San Diego., Cheung VJ; Department of Neurosurgery, University of California, San Diego., Santiago-Dieppa DR; Department of Neurosurgery, University of California, San Diego., Pannell JS; Department of Neurosurgery, University of California, San Diego., Khalessi AA; Department of Neurosurgery, University of California, San Diego.
Jazyk: angličtina
Zdroj: Journal of visualized experiments : JoVE [J Vis Exp] 2017 Oct 20 (128). Date of Electronic Publication: 2017 Oct 20.
DOI: 10.3791/55522
Abstrakt: Arteriovenious malformations (AVMs) are associated with significant morbidity and mortality, and have a rupture risk of ~3% per year. Treatment of AVMs must be tailored specifically to the lesion, with surgical resection being the gold standard for small, accessible lesions. Pre-operative embolization of AVMs can reduce nidal blood flow and remove high-risk AVM features such as intranidal or venous aneurysms, thereby simplifying a challenging neurosurgical procedure. Herein, we describe our approach for the staged endovascular embolization and open resection of AVMs, and highlight the advantages of having a comprehensively trained neurovascular surgeon leading a multi-disciplinary clinical team. This includes planning the craniotomy and resection to immediately follow the final embolization stage, thereby using a single session of anesthesia for aggressive embolization, and rapid resection. Finally, we provide a representative case of a 22-year-old female with an unruptured right frontal AVM diagnosed during a seizure workup, who was successfully treated via staged embolizations followed by open surgical resection.
Databáze: MEDLINE