| Autor: |
Gornatti-Churria CD; Cátedra de Patología de Aves y Pilíferos y Laboratorio de Diagnóstico de Enfermedades de las Aves y los Pilíferos, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Provincia de Buenos Aires, Argentina (Gornatti-Churria).; California Animal Health and Food Safety Laboratory System, Turlock (Crispo), University of California-Davis, CA.; Tulare (Shivaprasad), University of California-Davis, CA.; San Bernardino (Uzal) branches, University of California-Davis, CA., Crispo M; Cátedra de Patología de Aves y Pilíferos y Laboratorio de Diagnóstico de Enfermedades de las Aves y los Pilíferos, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Provincia de Buenos Aires, Argentina (Gornatti-Churria).; California Animal Health and Food Safety Laboratory System, Turlock (Crispo), University of California-Davis, CA.; Tulare (Shivaprasad), University of California-Davis, CA.; San Bernardino (Uzal) branches, University of California-Davis, CA., Shivaprasad HL; Cátedra de Patología de Aves y Pilíferos y Laboratorio de Diagnóstico de Enfermedades de las Aves y los Pilíferos, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Provincia de Buenos Aires, Argentina (Gornatti-Churria).; California Animal Health and Food Safety Laboratory System, Turlock (Crispo), University of California-Davis, CA.; Tulare (Shivaprasad), University of California-Davis, CA.; San Bernardino (Uzal) branches, University of California-Davis, CA., Uzal FA; Cátedra de Patología de Aves y Pilíferos y Laboratorio de Diagnóstico de Enfermedades de las Aves y los Pilíferos, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Provincia de Buenos Aires, Argentina (Gornatti-Churria).; California Animal Health and Food Safety Laboratory System, Turlock (Crispo), University of California-Davis, CA.; Tulare (Shivaprasad), University of California-Davis, CA.; San Bernardino (Uzal) branches, University of California-Davis, CA. |
| Abstrakt: |
Gangrenous dermatitis (GD) is a disease of chickens and turkeys that causes severe economic losses in the poultry industry worldwide. Clostridium septicum, Clostridium perfringens type A, and occasionally Clostridium sordellii are considered the main causes of GD, although Staphylococcus aureus and other aerobic bacteria may also be involved in some cases of the disease. GD has become one of the most significant diseases of commercial turkeys in the United States. Several infectious and/or environmental immunosuppressive factors can predispose to GD. Skin lesions are considered to be the main portal of entry of the microorganism(s) involved. GD is characterized by acute onset of mortality associated with gross skin and subcutaneous tissue lesions consisting of variable amounts of serosanguineous exudate together with emphysema and hemorrhages. The underlying skeletal muscle can also be involved. Ulceration of the epidermis may be also noticed in cases complicated with S. aureus. Microscopically, necrosis of the epidermis and dermis, and subcutaneous edema and emphysema are commonly observed. Gram-positive rods can be identified within the subcutis and skeletal muscles, usually associated with minimal inflammatory infiltrate. A presumptive diagnosis of GD can be made based on history, clinical signs, and gross anatomic and microscopic lesions. However, confirmation should be based on demonstration of the causative agents by culture, PCR, immunohistochemistry, and/or fluorescent antibody tests. |
