Laser and Platelet-Rich Plasma to treat Medication-Related Osteonecrosis of the Jaws (MRONJ): a case report.

Autor: Fornaini C; Odontostomatology and Maxillo-Facial Surgery Unit - Special care dentistry 'Guglielmo da Saliceto' Hospital - Piacenza - Italy.; UFR Odontologie - Université de Nice 'Sophia Antipolis' - Nice - France., Cella L; Odontostomatology and Maxillo-Facial Surgery Unit - Special care dentistry 'Guglielmo da Saliceto' Hospital - Piacenza - Italy., Oppici A; Odontostomatology and Maxillo-Facial Surgery Unit - Special care dentistry 'Guglielmo da Saliceto' Hospital - Piacenza - Italy., Parlatore A; Immunohematology and Transfusion Medicine 'Guglielmo da Saliceto Hospital - Piacenza - Italy., Clini F; Odontostomatology and Maxillo-Facial Surgery Unit - Special care dentistry 'Guglielmo da Saliceto' Hospital - Piacenza - Italy., Fontana M; Odontostomatology and Maxillo-Facial Surgery Unit - Special care dentistry 'Guglielmo da Saliceto' Hospital - Piacenza - Italy., Lagori G; Odontostomatology and Maxillo-Facial Surgery Unit - Special care dentistry 'Guglielmo da Saliceto' Hospital - Piacenza - Italy., Merigo E; Odontostomatology and Maxillo-Facial Surgery Unit - Special care dentistry 'Guglielmo da Saliceto' Hospital - Piacenza - Italy.; UFR Odontologie - Université de Nice 'Sophia Antipolis' - Nice - France.
Jazyk: angličtina
Zdroj: Laser therapy [Laser Ther] 2017 Sep 30; Vol. 26 (3), pp. 223-227.
DOI: 10.5978/islsm.17-CR-04
Abstrakt: Aims: The appropriate management of Medication-Related OsteoNecrosis of the Jaw (MRONJ) is still a challenge for dentists and oral surgeons and in these last years high-technology instruments have been proposed at the different steps of interventions, also combined with promoters of tissue repair.The aim of this report is to show the advantages of a combined approach (laser and PRP) for the treatment of MRONJ.
Methods: It is described the case of a patient positive for MRONJ observed at the Odontostomatology and Maxillo-Facial Surgery Unit of the Hospital of Piacenza where surgical approach was performed by using different devices: Er:YAG laser (2940 nm) to remove and vaporize necrotic hard tissue until bleeding bone; Platelet-Rich Plasma (PRP) to stimulate hard and soft tissue healing; diode laser (808 nm) to biostimulate the surgical site.
Results: At the time of suture removal, wound closure was observed and the complete healing of the MRONJ site was observed for the 2 years follow up.
Conclusion: This case may suggest that this kind of combined approach during all the steps of MRONJ treatment allows to perform a faster and less invasive surgery with a more comfortable postoperative healing process and it represents an innovative approach in this severe adverse event.
Databáze: MEDLINE