School-Based Influenza Vaccination: Health and Economic Impact of Maine's 2009 Influenza Vaccination Program.

Autor: Basurto-Dávila R; Los Angeles County Department of Public Health, Los Angeles, CA., Meltzer MI; Centers for Disease Control and Prevention, Atlanta, GA., Mills DA; University of New England, Portland, ME., Beeler Asay GR; Centers for Disease Control and Prevention, Atlanta, GA., Cho BH; Centers for Disease Control and Prevention, Atlanta, GA., Graitcer SB; Centers for Disease Control and Prevention, Atlanta, GA., Dube NL; Maine Department of Education, Augusta, ME., Thompson MG; Centers for Disease Control and Prevention, Atlanta, GA., Patel SA; Centers for Disease Control and Prevention, Atlanta, GA., Peasah SK; Mercer University, Atlanta, GA., Ferdinands JM; Centers for Disease Control and Prevention, Atlanta, GA., Gargiullo P; Centers for Disease Control and Prevention, Atlanta, GA., Messonnier M; Centers for Disease Control and Prevention, Atlanta, GA., Shay DK; Centers for Disease Control and Prevention, Atlanta, GA.
Jazyk: angličtina
Zdroj: Health services research [Health Serv Res] 2017 Dec; Vol. 52 Suppl 2, pp. 2307-2330.
DOI: 10.1111/1475-6773.12786
Abstrakt: Objective: To estimate the societal economic and health impacts of Maine's school-based influenza vaccination (SIV) program during the 2009 A(H1N1) influenza pandemic.
Data Sources: Primary and secondary data covering the 2008-09 and 2009-10 influenza seasons.
Study Design: We estimated weekly monovalent influenza vaccine uptake in Maine and 15 other states, using difference-in-difference-in-differences analysis to assess the program's impact on immunization among six age groups. We also developed a health and economic Markov microsimulation model and conducted Monte Carlo sensitivity analysis.
Data Collection: We used national survey data to estimate the impact of the SIV program on vaccine coverage. We used primary data and published studies to develop the microsimulation model.
Principal Findings: The program was associated with higher immunization among children and lower immunization among adults aged 18-49 years and 65 and older. The program prevented 4,600 influenza infections and generated $4.9 million in net economic benefits. Cost savings from lower adult vaccination accounted for 54 percent of the economic gain. Economic benefits were positive in 98 percent of Monte Carlo simulations.
Conclusions: SIV may be a cost-beneficial approach to increase immunization during pandemics, but programs should be designed to prevent lower immunization among nontargeted groups.
(© Health Research and Educational Trust.)
Databáze: MEDLINE
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