Green Tea Extract Increases the Expression of Genes Responsible for Regulation of Calcium Balance in Rat Slow-Twitch Muscles under Conditions of Exhausting Exercise.

Autor: Korf EA; I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, St. Petersburg, Russia., Kubasov IV; I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, St. Petersburg, Russia., Vonsky MS; Institute of Cytology of Russian Academy of Sciences, St. Petersburg, Russia., Novozhilov AV; I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, St. Petersburg, Russia., Runov AL; Institute of Cytology of Russian Academy of Sciences, St. Petersburg, Russia., Kurchakova EV; Institute of Cytology of Russian Academy of Sciences, St. Petersburg, Russia., Matrosova EV; I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, St. Petersburg, Russia., Tavrovskaya TV; I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, St. Petersburg, Russia., Goncharov NV; I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, St. Petersburg, Russia. ngoncharov@gmail.com.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2017 Nov; Vol. 164 (1), pp. 6-9. Date of Electronic Publication: 2017 Nov 09.
DOI: 10.1007/s10517-017-3913-9
Abstrakt: We studied the role of calcium-regulating structures of slow- (m. soleus, SOL) and fast-twitch (m. extensor digitorum longus, EDL) skeletal muscles of rats during adaptation to exhausting physical activity and the possibility of modulating this adaptation with decaffeinated green tea extract. It was established that EDL adaptation is mainly aimed at Са 2+ elimination from the sarcoplasm by Са-ATPase and its retention in the reticulum by calsequestrin. Administration of green tea extract increased endurance due to involvement of slow-twitch muscles whose adaptation is associated with enhanced expression of all the studied genes responsible for the regulation of Ca 2+ balance.
Databáze: MEDLINE
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