[Early and mid-term results of the transapical aortic valve Symetis Acurate TA: a viable solution in high-risk patients with severe vascular disease].

Autor:	Rescigno G; S.O.D. Cardiochirurgia., Fratesi MG; S.O.D. Cardiochirurgia., Aratari C; S.O.D. Cardiochirurgia., Moretti S; S.O.D. Cardiologia., Capestro F; S.O.D. Cardiochirurgia., Serenelli M; S.O.D. Cardiologia., Piangerelli L; S.O.D. Cardiologia., Delca A; S.O.D. Cardiochirurgia., Perna GP; S.O.D. Cardiologia., Capucci A; Clinica di Cardiologia, Ospedali Riuniti di Ancona., Di Eusanio M; S.O.D. Cardiochirurgia.
Jazyk:	italština
Zdroj:	Giornale italiano di cardiologia (2006) [G Ital Cardiol (Rome)] 2017 Oct; Vol. 18 (10), pp. 727-733.
DOI:	10.1714/2790.28262
Abstrakt:	Background: Aortic valve stenosis is the most common valvular disease in the elderly. Transcatheter aortic valve implantation represents a viable alternative to conventional aortic valve replacement. In our Department, the transapical approach is the preferred method in patients with severe peripheral vascular disease. The aim of this study was to analyze the early and midterm results of Symetis Acurate TA implantation in our series. Methods: From June 2013 to January 2017, 21 patients with severe peripheral vascular disease (11 male, mean age 78 ± 2.8 years) underwent transapical implantation of the Symetis Acurate TA device. Mean logistic EuroSCORE I was 21.9 ± 8.6, mean left ventricular ejection fraction was 51.9 ± 12.2%, and mean aortic gradient was 46.7 ± 12.3 mmHg. Valve implantation was performed through a left anterior minithoracotomy. Patients were followed up on a regular basis. Cardiac echocardiographic assessment was performed at 6 months post-implantation. Results: Valve implantation was successful in all patients. Valve sizes were as follows: 7 size S, 6 size M, and 8 size L. Two patients died before hospital discharge (9.5%). Among survivors, 2 patients showed more than mild aortic regurgitation at discharge. Mean aortic gradient was 13.1 ± 4.3 mmHg (p<0.01). Median follow-up was 11.3 months. Mean NYHA class at follow-up was 1.9 ± 0.4 (p<0.05). Mean actuarial survival was 80%. Conclusions: Our series, even if small, demonstrates that transapical implantation of the Symetis Acurate TA device represents a viable solution in patients with severe peripheral vascular disease carrying a high operative risk. The relatively high operative mortality may be attributable to the learning curve of our team.
Databáze:	MEDLINE
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