| Autor: |
Hawash YA; Medical Laboratory Department, Faculty of Applied Medical Science, Taif University, Taif, Saudi Arabia.; Clinical and Molecular Parasitology Department, National Liver Institute (NLI), Menoufia University, Shebin Al Koom, Menoufia, Egypt., Ismail KA; Medical Laboratory Department, Faculty of Applied Medical Science, Taif University, Taif, Saudi Arabia.; Parasitology Department, Faculty of Medicine, Ain-Shams University, Cairo, Egypt., Almehmadi M; Medical Laboratory Department, Faculty of Applied Medical Science, Taif University, Taif, Saudi Arabia. |
| Jazyk: |
angličtina |
| Zdroj: |
The Korean journal of parasitology [Korean J Parasitol] 2017 Oct; Vol. 55 (5), pp. 513-521. Date of Electronic Publication: 2017 Oct 31. |
| DOI: |
10.3347/kjp.2017.55.5.513 |
| Abstrakt: |
Infectious diarrhea is endemic in most developing countries. We aimed to investigate the protozoan, viral, and bacterial causes of acute diarrhea in Taif, Saudi Arabia. A cross-sectional prospective 1-year study was conducted on 163 diarrheal patients of various ages. Stool samples were collected, 1 per patient, and tested for 3 protozoa, 3 viruses, and 9 bacteria with the Luminex Gastrointestinal Pathogen Panel. Overall, 53.4% (87/163) of samples were positives (20.8% protozoa, 19.6% viruses, 2.8% bacteria, and 9.8% mixed). Rotavirus (19.6%), Giardia duodenalis (16.5%), and Cryptosporidium spp. (8.5%) were the mostly detected pathogens. Adenovirus 40/41 (4.2%), Salmonella (3%), Shiga toxin-producing Escherichia coli (3%), and Entamoeba histolytica (2.4%) were also detected. Norovirus GI/II, Vibrio cholerae, Yersinia enterocolitica, and Clostridium difficile toxin A/B were not detected in any patients. All pathogens were involved in coinfections except E. histolytica. Giardia (5.5%) and rotavirus (3%) were the most commonly detected in co-infections. Enterotoxigenic E. coli (2.4%), Campylobacter spp. (2.4%), E. coli 0157 (1.8%), and Shigella spp. (1.2%) were detected in patients only as co-infections. Infections were more in children 0-4 years, less in adults <40 years, and least >40 years, with statistically significant differences in risk across age groups observed with rotavirus (P<0.001), Giardia (P=0.006), and Cryptosporidium (P=0.036) infections. Lastly, infections were not significantly more in the spring. This report demonstrates the high burden of various enteropathogens in the setting. Further studies are needed to define the impact of these findings on the clinical course of the disease. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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