| Autor: |
Yam XY; School of Biological Sciences, Nanyang Technological University, 637551, Singapore. xueyan06@gmail.com prpreiser@ntu.edu.sg., Preiser PR |
| Jazyk: |
angličtina |
| Zdroj: |
Molecular bioSystems [Mol Biosyst] 2017 Nov 21; Vol. 13 (12), pp. 2498-2508. |
| DOI: |
10.1039/c7mb00502d |
| Abstrakt: |
Host immune evasion is a key strategy for the continual survival of many microbial pathogens including Apicomplexan protozoan: Plasmodium spp., the causative agent of Malaria. The malaria parasite has evolved a variety of mechanisms to evade the host immune responses within its two hosts: the female Anopheles mosquito vector and vertebrate host. In this review, we will focus on the molecular mechanisms of the immune evasion strategies used by the Plasmodium parasite at the blood stage which is responsible for the clinical manifestations of human malaria. We also aim to provide some insights on the potential targets for malaria interventions through the recent advancement in understanding the molecular biology of the parasite. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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