Hepatitis C Virus Exposure Rate among Health-care Workers in Rural Lower Egypt Governorates.

Autor:	Elbahrawy A; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Elwassief A; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Abdallah AM; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Kasem A; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Mostafa S; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Makboul K; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Ali MS; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Alashker A; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Eliwa AM; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Shahbah H; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Othman MA; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Morsy MH; Department of Microbiology, Faculty of Science, Al-Azhar University, Cairo, Egypt., Abdelbaseer MA; Department of Clinical Pathology, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt., Abdelhafeez H; Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt.
Jazyk:	angličtina
Zdroj:	Journal of translational internal medicine [J Transl Int Med] 2017 Sep 30; Vol. 5 (3), pp. 164-168. Date of Electronic Publication: 2017 Sep 30 (Print Publication: 2017).
DOI:	10.1515/jtim-2017-0024
Abstrakt:	Background and Objectives: Studies on hepatitis C virus (HCV) in Egypt supported a strong role for various exposures in the health-care setting. In this study, we attempted to estimate the frequency of HCV exposure among Egyptian health-care workers (HCWs). Methods: Five hundred and sixty-four (564) HCWs were included in this study. Two hundred and fifty-eight (45.74%) were health-care providers and 306 (54.25%) were non-health-care providers. All HCWs completed both the study questionnaire and provided a blood sample for anti-HCV testing by third-generation enzyme-linked immunosorbent assay. Subsequently, anti-HCV-positive samples were tested for HCV RNA using nested polymerase chain reaction (PCR). Results: The mean age of included HCWs was 33.0 ± 9.8 years; of them, 319 (56.56%) were males and 245 (43.44%) were females. The mean duration of health-care work was 9.3 ± 6.7 years. The frequency of antibody against hepatitis C virus (anti-HCV) among included HCWs was 8.7% ( n = 49). Old age and prolonged duration of health-care work were significantly associated with anti-HCV seropositivity. Forty (81.63%) of 49 with anti-HCV-positive HCWs had positive hepatitis C viremia. The frequency of HCV RNA positivity increased with age. The frequency of eradicated past infection among nurses (36.85%) was markedly higher than that (6.7%) detected in non-health-care providers. Conclusion: High rate of HCV infection is detected in Egyptian HCWs in rural Lower Egypt governorates. Health-care providers seem to eradicate HCV infection more frequently than non-health-care providers. National screening and treatment of infected HCWs are recommended. Competing Interests: Conflict of Interest: All other authors declare no competing interests. Ethical approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments. Informed consent: Informed consent was obtained from all individual participants included in the study.
Databáze:	MEDLINE
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