| Autor: |
Tae CH; Department of Health Promotion Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea., Moon CM; Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea. mooncm27@ewha.ac.kr., Jung SA; Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea., Eun CS; Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Republic of Korea., Park JJ; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Seo GS; Department of Internal Medicine, Digestive Disease Research Institute, Wonkwang University College of Medicine, Iksan, Republic of Korea., Cha JM; Department of Internal Medicine, Kyung Hee University Hospital at Gang Dong, Kyung Hee University School of Medicine, Seoul, Republic of Korea., Park SC; Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Republic of Korea., Chun J; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee HJ; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea., Jung Y; Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan, Republic of Korea., Kim JO; Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul Hospital, Seoul, Republic of Korea., Joo YE; Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea., Boo SJ; Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Republic of Korea., Il Park D; Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. |
| Abstrakt: |
We aimed to evaluate whether obesity was associated with a certain clinicopathologic characteristics of metachronous CRA. This retrospective longitudinal cohort study included 2,904 subjects who had at least one resected CRA at index colonoscopy and who subsequently underwent one or more surveillance colonoscopies within 5 years. Of the 2,904 subjects, 60.9% (n = 1,769) were normal, 35.8% (n = 1,040) were overweight, and 3.3% (n = 95) were obese. Patients with any metachronous CRA were 53.7% (n = 1,559). In multivariate analyses, higher BMI at index colonoscopy was significantly associated with any metachronous CRA (overweight, OR = 1.07; obese, OR = 1.82; p for trend = 0.049). Regarding the multiplicity, the ORs of ≥ 3, ≥ 4 and ≥ 5 metachronous CRAs significantly increased as index BMI increased (p for trend < 0.001, = 0.007 and = 0.004, respectively). In negative binomial regression regarding the incidence for total number of metachronous CRA, the higher BMI the subject has at the time of index colonoscopy, the more metachronous CRAs the subject will have at the surveillance colonoscopy (p for trend = 0.016). Higher index BMI was significantly associated with the risk of multiple metachronous CRAs on surveillance colonoscopy within 5 years. |
