Histopathology, vitellogenin and chemical body burden in mosquitofish (Gambusia holbrooki) sampled from six river sites receiving a gradient of stressors.

Autor: Scott PD; Australian Rivers Institute, Griffith School of Environment, Griffith University, Queensland 4222, Australia., Coleman HM; School of Civil & Environmental Engineering, University of New South Wales, New South Wales 2052, Australia., Khan S; School of Civil & Environmental Engineering, University of New South Wales, New South Wales 2052, Australia., Lim R; School of Life Sciences, University of Technology Sydney, PO Box 123, Broadway, New South Wales 2007, Australia., McDonald JA; School of Civil & Environmental Engineering, University of New South Wales, New South Wales 2052, Australia., Mondon J; School of Life and Environmental Sciences, Centre for Integrative Ecology, Deakin University, Victoria 3280, Australia., Neale PA; Australian Rivers Institute, Griffith School of Environment, Griffith University, Queensland 4222, Australia., Prochazka E; Australian Rivers Institute, Griffith School of Environment, Griffith University, Queensland 4222, Australia., Tremblay LA; Cawthron Institute, 98 Halifax St. East, Nelson 7042, New Zealand; School of Biological Sciences, University of Auckland, PO Box 92019, Auckland 1142, New Zealand., Warne MSJ; Australian Rivers Institute, Griffith School of Environment, Griffith University, Queensland 4222, Australia; Water Quality and Investigations, Department of Science, Information Technology and Innovation, Queensland Government, Queensland 4001, Australia., Leusch FDL; Australian Rivers Institute, Griffith School of Environment, Griffith University, Queensland 4222, Australia. Electronic address: f.leusch@griffith.edu.au.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2018 Mar; Vol. 616-617, pp. 1638-1648. Date of Electronic Publication: 2017 Nov 01.
DOI: 10.1016/j.scitotenv.2017.10.148
Abstrakt: There are over 40,000 chemical compounds registered for use in Australia, and only a handful are monitored in the aquatic receiving environments. Their effects on fish species in Australia are largely unknown. Mosquitofish (Gambusia holbrooki) were sampled from six river sites in Southeast Queensland identified as at risk from a range of pollutants. The sites selected were downstream of a wastewater treatment plant discharge, a landfill, two agricultural areas, and two sites in undeveloped reaches within or downstream of protected lands (national parks). Vitellogenin analysis, histopathology of liver, kidney and gonads, morphology of the gonopodium, and chemical body burden were measured to characterize fish health. Concentrations of trace organic contaminants (TrOCs) in water were analyzed by in vitro bioassays and chemical analysis. Estrogenic, anti-estrogenic, anti-androgenic, progestagenic and anti-progestagenic activities and TrOCs were detected in multiple water samples. Several active pharmaceutical ingredients (APIs), industrial compounds, pesticides and other endocrine active compounds were detected in fish carcasses at all sites, ranging from <4-4700ng/g wet weight, including the two undeveloped sites. While vitellogenin protein was slightly increased in fish from two of the six sites, the presence of micropollutants did not cause overt sexual endocrine disruption in mosquitofish (i.e., no abnormal gonads or gonopodia). A correlation between lipid accumulation in the liver with total body burden warrants further investigation to determine if exposure to low concentrations of TrOCs can affect fish health and increase stress on organs such as the liver and kidneys via other mechanisms, including disruption of non-sexual endocrine axes involved in lipid regulation and metabolism.
(Copyright © 2017 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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