Evaluation of bovine beta casein polymorphism in two dairy farms located in northern Italy.

Autor: Massella E; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (BO)., Piva S; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (BO)., Giacometti F; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (BO)., Liuzzo G; A.U.S.L of Modena Carpi district, Carpi (MO)., Zambrini AV; Department of Quality, Innovation, Safety, Environment, Granarolo S.p.A., Bologna, Italy., Serraino A; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (BO).
Jazyk: angličtina
Zdroj: Italian journal of food safety [Ital J Food Saf] 2017 Sep 29; Vol. 6 (3), pp. 6904. Date of Electronic Publication: 2017 Sep 29 (Print Publication: 2017).
DOI: 10.4081/ijfs.2017.6904
Abstrakt: Bovine beta casein A1 is one of the most common variants in dairy cattle breeds; it is considered a risk factor in milk intolerance and in other important human diseases, because of the bioactive peptide beta casomorphin-7 (BCM7) produced by raw or processed A1-milk, but not by A2-milk, during digestion. The aim of this study was to perform a cheap and rapid method to investigate beta casein polymorphism in copious animals. The study included 2 dairy farms with a totally of 1230 cows. Beta casein genotypes were estimated evaluating Exon 7 region of bovine beta casein gene (CSN2) by sequences analysis. In the population included in the study 5 variants (A1, A2, B, F, I) and 13 genotypes (A1A1, A1A2, A1B, A1F, A1I, A2A2, A2B, A2F, A2I, BB, BF, BI, FI) were detected. The method showed high sensibility and specificity, resulted low-cost and few time consuming.
Competing Interests: Conflicts of interest: authors declare no potential conflict of interest.
Databáze: MEDLINE