Nasopharyngeal metagenomic deep sequencing data, Lancaster, UK, 2014-2015.

Autor:	Atkinson KV; Division of Biomedical & Life Sciences, Faculty of Health & Medicine, Lancaster University, Lancaster LA1 4YT, UK., Bishop LA; Division of Biomedical & Life Sciences, Faculty of Health & Medicine, Lancaster University, Lancaster LA1 4YT, UK.; Royal Lancaster Infirmary, Ashton Road, Lancaster LA1 4RP, UK., Rhodes G; Centre for Ecology & Hydrology, Lake Ecosystems Group, Lancaster Environment Centre, Lancaster University, Lancaster LA1 4AP, UK., Salez N; UMR_D 190, Emergence des Pathologies Virales, Aix-Marseille University, 27 Bd Jean Moulin, Marseille cedex 05 13005, France., McEwan NR; Institute of Biological, Environmental & Rural Sciences, Aberystwyth University, Aberystwyth SY23 3DA, UK., Hegarty MJ; Institute of Biological, Environmental & Rural Sciences, Aberystwyth University, Aberystwyth SY23 3DA, UK., Robey J; Queen Square Medical Practice, 2 Queen Square, Lancaster LA1 1RP, UK., Harding N; Queen Square Medical Practice, 2 Queen Square, Lancaster LA1 1RP, UK., Wetherell S; Queen Square Medical Practice, 2 Queen Square, Lancaster LA1 1RP, UK., Lauder RM; Division of Biomedical & Life Sciences, Faculty of Health & Medicine, Lancaster University, Lancaster LA1 4YT, UK., Pickup RW; Division of Biomedical & Life Sciences, Faculty of Health & Medicine, Lancaster University, Lancaster LA1 4YT, UK., Wilkinson M; Royal Lancaster Infirmary, Ashton Road, Lancaster LA1 4RP, UK., Gatherer D; Division of Biomedical & Life Sciences, Faculty of Health & Medicine, Lancaster University, Lancaster LA1 4YT, UK.
Jazyk:	angličtina
Zdroj:	Scientific data [Sci Data] 2017 Oct 24; Vol. 4, pp. 170161. Date of Electronic Publication: 2017 Oct 24.
DOI:	10.1038/sdata.2017.161
Abstrakt:	Nasopharyngeal swabs were taken from volunteers attending a general medical practice and a general hospital in Lancaster, UK, and at Lancaster University, in the winter of 2014-2015. 51 swabs were selected based on high RNA yield and allocated to deep sequencing pools as follows: patients with chronic obstructive pulmonary disease; asthmatics; adults with no respiratory symptoms; adults with feverish respiratory symptoms; adults with respiratory symptoms and presence of antibodies against influenza C; paediatric patients with respiratory symptoms (2 pools); adults with influenza C infection (2 pools), giving a total of 9 pools. Illumina sequencing was performed, with data yields per pool in the range of 345.6 megabases to 14 gigabases after removal of reads aligning to the human genome. The data were deposited in the Sequence Read Archive at NCBI, and constitute a resource for study of the viral, bacterial and fungal metagenome of the human nasopharynx in healthy and diseased states and comparison with other metagenomic studies on the human respiratory tract.
Databáze:	MEDLINE
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