Quantitative analysis of antibiotic usage in British sheep flocks.

Autor: Davies P; School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK., Remnant JG; School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK., Green MJ; School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK., Gascoigne E; Synergy Farm Health LTD, West Hill Barns, Evershot, Dorchester, UK.; RAFT Solutions Ltd, Mill Farm, Ripon, UK., Gibbon N; Belmont Farm & Equine Ltd, Hereford, UK., Hyde R; School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK., Porteous JR; Browne & McKinney, Broughton-in-Furness, UK., Schubert K; Torch Farm and Equine, Bideford, UK., Lovatt F; School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK., Corbishley A; Dairy Herd Health and Productivity Service, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, UK.; Division of Immunity and Infection, The Roslin Institute, The University of Edinburgh, Midlothian, UK.
Jazyk: angličtina
Zdroj: The Veterinary record [Vet Rec] 2017 Nov 11; Vol. 181 (19), pp. 511. Date of Electronic Publication: 2017 Oct 19.
DOI: 10.1136/vr.104501
Abstrakt: The aim of this study was to examine the variation in antibiotic usage between 207 commercial sheep flocks using their veterinary practice prescribing records. Mean and median prescribed mass per population corrected unit (mg/PCU) was 11.38 and 5.95, respectively and closely correlated with animal defined daily dose (ADDD) 1.47 (mean), 0.74 (median) (R 2 =0.84, P<0.001). This is low in comparison with the suggested target (an average across all the UK livestock sectors) of 50 mg/PCU. In total, 80 per cent of all antibiotic usage occurred in the 39 per cent of flocks where per animal usage was greater than 9.0 mg/PCU. Parenteral antibiotics, principally oxytetracycline, represented 82 per cent of the total prescribed mass, 65.5 per cent of antibiotics (mg/PCU) were prescribed for the treatment of lameness. Oral antibiotics were prescribed to 49 per cent of flocks, 64 per cent of predicted lamb crop/farm. Lowland flocks were prescribed significantly more antibiotics than hill flocks. Variance partitioning apportioned 79 per cent of variation in total antibiotic usage (mg/PCU) to the farm level and 21 per cent to the veterinary practice indicating that veterinary practices have a substantial impact on overall antimicrobial usage. Reducing antibiotic usage in the sheep sector should be possible with better understanding of the drivers of high usage in individual flocks and of veterinary prescribing practices.
Competing Interests: Competing interests: None declared.
(© British Veterinary Association (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.)
Databáze: MEDLINE
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