Orbital T-cell lymphoma versus lupus panniculitits: a T-cell-mediated spectrum of orbital lymphoproliferative disease.

Autor: Huggins AB; a Wills Eye Hospital, Thomas Jefferson University Hospital , Philadelphia , PA , USA., Kim C; b The Oculoplastic and Orbital Surgery Department of Wills Eye Hospital , Thomas Jefferson University Hospital , Philadelphia , PA , USA., Rabinowitz MP; b The Oculoplastic and Orbital Surgery Department of Wills Eye Hospital , Thomas Jefferson University Hospital , Philadelphia , PA , USA.
Jazyk: angličtina
Zdroj: Orbit (Amsterdam, Netherlands) [Orbit] 2018 Apr; Vol. 37 (2), pp. 102-104. Date of Electronic Publication: 2017 Oct 17.
DOI: 10.1080/01676830.2017.1383460
Abstrakt: This is a case description of a single male patient found to have T-cell-mediated inflammation and lymphoproliferation of the orbit. Chronic T-cell-mediated inflammatory disease can pose a diagnostic challenge particularly in its differentiation from a neoplastic process. The histopathology in this case demonstrated features of both lupus erythematosus panniculitis and features of orbital T-cell lymphoma. While both are rare, lupus erythematosus panniculitis of the orbit is even more exceptional; this patient's indolent, chronic relapsing course distinguished itself from the typical aggression of orbital T-cell lymphoma. We believe this rare case may actually represent an example of a newly described disease spectrum that incorporates lupus erythematosus panniculitis as well as subcutaneous panniculitis-like T-cell lymphoma.
Databáze: MEDLINE
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