The influence of mitomycin C concentration on the outcome of trabeculectomy in uveitic glaucoma.

Autor: Almobarak FA; Department of Ophthalmology, College of Medicine, King Saud University, P.O. Box 245, Riyadh, 11411, Saudi Arabia. falmobarak@ksu.edu.sa.; Glaucoma Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia. falmobarak@ksu.edu.sa., Alharbi AH; Glaucoma Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.; King Abdullah Medical City, Makkah, Saudi Arabia., Morales J; Glaucoma Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia., Aljadaan I; Glaucoma Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Jazyk: angličtina
Zdroj: International ophthalmology [Int Ophthalmol] 2018 Dec; Vol. 38 (6), pp. 2371-2379. Date of Electronic Publication: 2017 Oct 14.
DOI: 10.1007/s10792-017-0737-6
Abstrakt: Purpose: To evaluate the influence of mitomycin C (MMC) concentration on the outcome of trabeculectomy in uveitic glaucoma.
Methods: Retrospective comparative study included 50 patients who underwent MMC-enhanced trabeculectomy for uncontrolled uveitic glaucoma. Patients were divided into two groups based on the concentration of MMC used during trabeculectomy (high [0.04%] or low [0.02%]). The main outcome measures were: the intraocular pressure (IOP), the number of antiglaucoma medications, the need for further glaucoma surgeries, and trabeculectomy success.
Results: There were no differences in the IOP nor antiglaucoma medications. The success rates were 76.0 and 68.0%, while the failure rates were 24.0 and 32.0% in the 0.02 and 0.04% MMC groups, respectively.
Conclusion: Trabeculectomy augmented with low (0.02%) MMC concentration seems to have comparable outcomes in uveitic glaucoma compared with high (0.04%) concentration.
Databáze: MEDLINE
Externí odkaz: