Chikungunya fever outbreak identified in North Bali, Indonesia.

Autor:	Sari K; Faculty of Medicine and Health Sciences, Warmadewa University, Denpasar, Bali, Indonesia80239., Myint KSA; Emerging Virus Research Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia10430., Andayani AR; Bali Provincial Health Office, Denpasar, Bali, Indonesia80234., Adi PD; Bali Provincial Health Office, Denpasar, Bali, Indonesia80234., Dhenni R; Emerging Virus Research Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia10430., Perkasa A; Emerging Virus Research Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia10430., Ma'roef CN; Emerging Virus Research Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia10430., Witari NPD; Faculty of Medicine and Health Sciences, Warmadewa University, Denpasar, Bali, Indonesia80239., Megawati D; Faculty of Medicine and Health Sciences, Warmadewa University, Denpasar, Bali, Indonesia80239., Powers AM; Centers for Disease Control and Prevention, Fort Collins, CO, USA, USA., Jaya UA; Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia10430.
Jazyk:	angličtina
Zdroj:	Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 2017 Jul 01; Vol. 111 (7), pp. 325-327.
DOI:	10.1093/trstmh/trx054
Abstrakt:	Background: Chikungunya virus (CHIKV) infections have been reported sporadically within the last 5 years in several areas of Indonesia including Bali. Most of the reports, however, have lacked laboratory confirmation. Method: A recent fever outbreak in a village in the North Bali area was investigated using extensive viral diagnostic testing including both molecular and serological approaches. Results and Conclusions: Ten out of 15 acute febrile illness samples were confirmed to have CHIKV infection by real-time PCR or CHIKV-specific IgM enzyme-linked immunosorbent assay (ELISA). The outbreak strain belonged to the Asian genotype with highest homology to other CHIKV strains currently circulating in Indonesia. The results are of public health concern particularly because Bali is a popular tourist destination in Indonesia and thereby the potential to spread the virus to non-endemic areas is high. Genbank Accession Numbers: KY885022, KY885023, KY885024, KY885025, KY885026, KY885027. (© The Author 2017. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
Databáze:	MEDLINE
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