Association between neuroendocrine tumor of the ileum and two colonic primary malignancies. A case report and review of literature.

Autor: Napolitano L, D'Alessandro V, Risio D, Marinelli C, Cianci R, Innocenti P
Jazyk: angličtina
Zdroj: Annali italiani di chirurgia [Ann Ital Chir] 2017 Oct 04; Vol. 6. Date of Electronic Publication: 2017 Oct 04.
Abstrakt: Background: A high rate of association between neuroendocrine tumors (NETs) and secondary primary malignancy (SPM) has been described in literature and this association can occur either in a synchronous or a metachronous presentation. A wide range of hypothesis has been postulated to explain the high rate of association between NETs and SPM, without definitive conclusions.
Case Presentation: We report a case of an ileal neuroendocrine tumor found incidentally at the histologic examination of the surgical specimen in a 72 years old male underwent to right hemi colectomy for two colic adenomatous polips with high grade dysplasia.
Conclusion: Large multicentric epidemiological studies should be considered to assess the association between NETs and SPM.
Key Words: Neuroendocrine tumors (NETs), Progression-Free Survival (PFS), Secondary primary malignancy (SPM).
Databáze: MEDLINE