[Transcranial direct current stimulation for the treatment of fibromyalgia: a systematic review].

Autor: Deus-Yela J; Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana; Universitat Autonoma de Barcelona, Bellaterra, Espana; CRC-Mar Hospital del Mar, Barcelona, Espana, Soler MD; Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana, Pelayo-Vergara R; Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana, Vidal-Samso J; Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana
Jazyk: Spanish; Castilian
Zdroj: Revista de neurologia [Rev Neurol] 2017 Oct 16; Vol. 65 (8), pp. 353-360.
Abstrakt: Introduction: Fibromyalgia is a multisymptomatic diffuse chronic musculoskeletal pain syndrome with evidence of central nervous system dysfunction. Accordingly, non-invasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) may be a complementary therapeutic resource to reduce pain perception.
Aims: To review the potential effectiveness of tDCS to reduce pain in fibromyalgia, to identify the most effective neurostimulation parameters and to delimit its safety.
Patients and Methods: Systematic review of prospective studies reported in PubMed and Cochrane reviews.
Results: The anodal tDCS of the left primary motor cortex, at 2mA for 20 minutes with 35 cm2 electrodes on five consecutive days, provides better results in reducing pain (14-59%), and improving sleep quality, with greater accentuation on the fifth day. The clinical improvement persists up to a minimum of 60 days (11-20% reduction of pain). Adverse effects are well tolerated and few.
Conclusions: The experience with tDCS in fibromyalgia is still limited. However, the anodal tDCS in the left primary motor cortex can be recommended with level B (probable therapeutic efficacy) and appears to act through the modification of the sensorial processing of the pain of thalamic inhibitory circuitry.
Databáze: MEDLINE