[Transcranial direct current stimulation for the treatment of fibromyalgia: a systematic review].
Autor: | Deus-Yela J; Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana; Universitat Autonoma de Barcelona, Bellaterra, Espana; CRC-Mar Hospital del Mar, Barcelona, Espana, Soler MD; Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana, Pelayo-Vergara R; Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana, Vidal-Samso J; Institut de Neurorehabilitacio Guttmann-UAB, 08916 Badalona, Espana |
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Jazyk: | Spanish; Castilian |
Zdroj: | Revista de neurologia [Rev Neurol] 2017 Oct 16; Vol. 65 (8), pp. 353-360. |
Abstrakt: | Introduction: Fibromyalgia is a multisymptomatic diffuse chronic musculoskeletal pain syndrome with evidence of central nervous system dysfunction. Accordingly, non-invasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) may be a complementary therapeutic resource to reduce pain perception. Aims: To review the potential effectiveness of tDCS to reduce pain in fibromyalgia, to identify the most effective neurostimulation parameters and to delimit its safety. Patients and Methods: Systematic review of prospective studies reported in PubMed and Cochrane reviews. Results: The anodal tDCS of the left primary motor cortex, at 2mA for 20 minutes with 35 cm2 electrodes on five consecutive days, provides better results in reducing pain (14-59%), and improving sleep quality, with greater accentuation on the fifth day. The clinical improvement persists up to a minimum of 60 days (11-20% reduction of pain). Adverse effects are well tolerated and few. Conclusions: The experience with tDCS in fibromyalgia is still limited. However, the anodal tDCS in the left primary motor cortex can be recommended with level B (probable therapeutic efficacy) and appears to act through the modification of the sensorial processing of the pain of thalamic inhibitory circuitry. |
Databáze: | MEDLINE |
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