Paraduodenal pancreatitis as a mimicker of pancreatic adenocarcinoma: MRI evaluation.

Autor: Boninsegna E; Department of Radiology, Policlinico G.B. Rossi, University of Verona, Italy. Electronic address: boninsegnae@gmail.com., Negrelli R; Department of Radiology, Policlinico G.B. Rossi, University of Verona, Italy., Zamboni GA; Department of Radiology, Policlinico G.B. Rossi, University of Verona, Italy., Tedesco G; Department of Radiology, Policlinico G.B. Rossi, University of Verona, Italy., Manfredi R; Department of Radiology, Policlinico A. Gemelli, Catholic University, Rome, Italy., Pozzi Mucelli R; Department of Radiology, Policlinico G.B. Rossi, University of Verona, Italy.
Jazyk: angličtina
Zdroj: European journal of radiology [Eur J Radiol] 2017 Oct; Vol. 95, pp. 236-241. Date of Electronic Publication: 2017 Aug 31.
DOI: 10.1016/j.ejrad.2017.08.031
Abstrakt: Purpose: To evaluate the MRI features of paraduodenal pancreatitis (PDP) and to define useful signs to differentiate PDP from pancreatic ductal adenocarcinoma (PDAC).
Material and Methods: We reviewed the MRI scans of 56 patients, 28 affected by PDP and 28 by PDAC, all pathologically proven. The following parameters were evaluated: signal intensity of the lesion on T1-, T2-WI, DWI (b800) and after contrast medium administration; presence of cysts; dilation of common hepatic duct and main pancreatic duct; focal thickening of the second portion of the duodenum; maximum diameter and volume of the lesion.
Results: Both PDPs and PDACs were more frequently hypointense on T1-WI, iso-hyperintense on T2-WI, hypointense in the pancreatic phase and iso-hypointense in the venous phase (p>0.05); in the delayed phase most PDP were hyperintense (p=0.0031); on DWI 71.4% PDPs were isointense and all PDACs were hyperintense (p=0.0041). Cystic components were present in 85.7% PDPs (p=0.0011); double duct sign was present in 50% PDACs (p=0.0048); focal thickening of the duodenum was depicted in 89.3 PDPs (p=0.0012). PDPs were larger than PDACs (p=0.0003).
Conclusion: The most suggestive signs of PDP are: signal hyperintensity in the delayed phase, isointensity on DWI, presence of cysts, focal thickening of the duodenum and large size of the lesion.
(Copyright © 2017 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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