| Autor: |
Sargenti CJ; Kaiser Permanente, Department of Pharmacy, San Diego, California., Rizos AL, Jeste DV |
| Jazyk: |
angličtina |
| Zdroj: |
The Psychiatric clinics of North America [Psychiatr Clin North Am] 1988 Mar; Vol. 11 (1), pp. 235-52. |
| Abstrakt: |
We have discussed major drug interactions involving neuroleptics and MAOIs. Interactions in the older patients are probably more frequent owing to the larger number of medications used. When interactions do occur in the elderly, the effects may be more severe and of a longer duration than those seen in younger patients. Many (but not all) drug-drug interactions are predictable, given a basic knowledge of the pharmacologic effects of the agents in question. In a number of cases, there are therapeutic alternatives to agents that have been reported to interact with psychotropic medications. The clinician should consider the likelihood of adverse drug interactions to be a significant concern as the age of the patient and the number of concurrently administered medications increase. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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