Novel Pathogens in Periodontal Microbiology.
| Autor: | Hiranmayi KV; Post Graduate Student, Department of Periodontics and Implantology, Drs S and NR Siddhartha Institute of Dental Sciences, Krishna District, Andhra Pradesh, India., Sirisha K; Reader, Department of Periodontics and Implantology, Drs S and NR Siddhartha Institute of Dental Sciences, Krishna District, Andhra Pradesh, India., Ramoji Rao MV; HOD, Department of Periodontics and Implantology, Drs S and NR Siddhartha Institute of Dental Sciences, Krishna District, Andhra Pradesh, India., Sudhakar P; Post Graduate Student, Department of Periodontics and Implantology, Drs S and NR Siddhartha Institute of Dental Sciences, Krishna District, Andhra Pradesh, India. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of pharmacy & bioallied sciences [J Pharm Bioallied Sci] 2017 Jul-Sep; Vol. 9 (3), pp. 155-163. |
| DOI: | 10.4103/jpbs.JPBS_288_16 |
| Abstrakt: | Periodontitis is a polymicrobial disease caused by complex interactions between distinct pathogens in a biofilm resulting in the destruction of periodontal tissues. It seems evident that unknown microorganisms might be involved in onset or progression of periodontitis. For many decades, research in the field of oral microbiology failed to identify certain subgingival microbiota due to technical limitations but, over a period of 12 years using molecular approaches and sequencing techniques, it became feasible to reveal the existence of new periodontal pathogens. Therefore, it is evident that in addition to conventional periodontal pathogens, other microbes might be involved in onset and progression of periodontitis. The novel pathogens enlisted under periodontal phylogeny include Cryptobacterium curtum , Dialister pneumosintes , Filifactor alocis , Mitsuokella dentalis , Slackia exigua , Selenomonas sputigena , Solobacterium moorei , Treponema lecithinolyticum , and Synergistes . The polymicrobial etiology of periodontitis has been elucidated by comprehensive techniques, and studies throwing light on the possible virulence mechanisms possessed by these novel periodontal pathogens are enlisted. Competing Interests: There are no conflicts of interest. |
| Databáze: | MEDLINE |
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