Presentation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in a Warthin Tumor: Case Report and Literature Review.

Autor: Jawad H; 1 Cork University Hospital, Cork, Ireland., McCarthy P; 1 Cork University Hospital, Cork, Ireland., O'Leary G; 2 South Infirmary Victoria University Hospital, Cork, Ireland., Heffron CC; 1 Cork University Hospital, Cork, Ireland.
Jazyk: angličtina
Zdroj: International journal of surgical pathology [Int J Surg Pathol] 2018 May; Vol. 26 (3), pp. 256-260. Date of Electronic Publication: 2017 Oct 04.
DOI: 10.1177/1066896917734371
Abstrakt: Warthin tumor is the second most common salivary gland neoplasm. It occurs more commonly in males than in females. Malignant transformation in Warthin tumor is a rare but well-recognized phenomenon; however, the development or presentation of lymphoma in a Warthin tumor is rare. An 80-year-old man presented with painless mass of the right parotid gland of 2 years duration with recent ulceration of the overlying skin and right cervical lymphadenopathy underwent a surgical resection of parotid mass and biopsy of the periglandular lymph nodes. The histological diagnosis was malignant lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma, present within the stroma of a Warthin tumor, and also present within the adjacent lymph node. This case is the third reported case describing a collision of Warthin tumor and chronic lymphocytic leukemia/small lymphocytic lymphoma. It also emphasizes the importance of careful examination of the lymphoid stroma of these tumors.
Databáze: MEDLINE