New Promising Strategies in Oncofertility.

Autor:	Hudson JN; Health Outcomes and Behavior Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL., Stanley NB; Health Outcomes and Behavior Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.; Department of Global Health, College of Public Health, University of South Florida., Nahata L; Division of Endocrinology and Center for Biobehavioral Health, The Research Institute at Nationwide Children's Hospital., Bowman-Curci M; Health Outcomes and Behavior Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL., Quinn GP; Health Outcomes and Behavior Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.; Department of Oncologic Science, Morsani College of Medicine, University of South Florida, Tampa, FL.
Jazyk:	angličtina
Zdroj:	Expert review of quality of life in cancer care [Expert Rev Qual Life Cancer Care] 2017; Vol. 2 (2), pp. 67-78. Date of Electronic Publication: 2017 Mar 28.
DOI:	10.1080/23809000.2017.1308808
Abstrakt:	Introduction: Approximately 70,000 adolescent and young adults (AYA) are diagnosed with cancer each year. While advancements in treatment have led to improved prognosis and survival for patients, these same treatments can adversely affect AYA reproductive capacity. Localized treatments such as surgery and radiation therapy may affect fertility by removing or damaging reproductive organs, and systemic therapies such as chemotherapy can be toxic to gonads, (ovaries and testicles), thus affecting fertility and/or endocrine function. This can be traumatic for AYA with cancer as survivors often express desire to have genetic children and report feelings of regret or depression as a result of infertility caused by cancer treatments. Areas Covered: Emerging technologies in the field of assisted reproductive technology offer new promise for preserving the reproductive capacity of AYA cancer patients prior to treatment as well as providing alternatives for survivors. The following review revisits contemporary approaches to fertility preservation as well newly developing technologies. Expert Commentary: There are several advances in ART that hold promise for patients and survivors. However there are challenges that inhibit uptake including poor communication between providers and patients about risks and fertility preservation options; high costs; and lack of insurance coverage for fertility preservation services.
Databáze:	MEDLINE
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