Effects of Sleep Deprivation on Spatial Learning and Memory in Juvenile and Young Adult Rats.

Autor: Ward CP; University of Houston-Clear Lake and Baylor College of Medicine., Wooden JI; University of Houston-Clear Lake., Kieltyka R; University of Houston-Clear Lake.
Jazyk: angličtina
Zdroj: Psychology & neuroscience [Psychol Neurosci] 2017 Mar; Vol. 10 (1), pp. 109-116.
DOI: 10.1037/pne0000075
Abstrakt: Sleepiness is commonly seen in adolescents and can negatively impact school performance. Little research has investigated the impact of sleepiness in juvenile animals on spatial learning. Sprague-Dawley juvenile (<30 days) and young adult (>60 days) rats were sleep deprived for 24 hours and tested, along with controls, in a water maze task. Sleep deprived juveniles were slower to learn the location of the hidden platform than controls; however, adult performance was not impaired. Sleep deprivation did not impair recall during a probe trial for either age group. Sleep deprivation prior to testing slowed spatial learning in juveniles but not adults.
Databáze: MEDLINE