Process and Outcome of Fecal Microbiota Transplants in Patients With Recurrent Clostridium difficile Infection: A Prospective Study.

Autor: Walton J; Janice Walton, BSN, RN, CGRN, is Staff Nurse, Endoscopy Lab, Memorial Hospital, Belleville, Illinois. Denise Burns, BSN, RN, CGRN, is Staff Nurse, Endoscopy Lab, Memorial Hospital, 4500 Memorial Drive, Belleville, Illinois. Kay E. Gaehle, PhD, RN, is Research Consultant, Memorial Hospital, and Associate Professor of Nursing at Southern Illinois University, Edwardsville, Belleville, Illinois., Burns D, Gaehle KE
Jazyk: angličtina
Zdroj: Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates [Gastroenterol Nurs] 2017 Sep/Oct; Vol. 40 (5), pp. 411-419.
DOI: 10.1097/SGA.0000000000000233
Abstrakt: The incidence of Clostridium difficile infection is on the rise worldwide, causing high mortality rates and costing patients, hospitals, and insurance companies millions of dollars annually. Fecal microbiota transplants successfully treat recurrent C. difficile infections unresponsive to standard pharmacologic treatment such as flagyl, vancomycin, or rifaximin. Evidence in the literature provided the foundation for the development and refinement of this fecal microbiota transplant protocol. During the initial phase of the project, the protocol included patient selection criteria, donor screening/selection, infection control, fecal processing and delivery, and patient pre and postprocedure education. This article highlights the second phase of prospective testing of a nurse-driven protocol to implement fecal microbiota transplantation in patients with recurrent C. difficile infection. All stages of the protocol are explained as well as rationale for component parts to achieve successful patient outcomes when the protocol is carefully followed.
Databáze: MEDLINE