Effect of Skin Application of Dorogov's Antiseptic-Stimulant on Behavioral Reactions in Rats.

Autor: Piavchenko GA; Center for Preclinical Research, Retinoids Company, Moscow, Russia. gennadii.piavchenko@yandex.ru.; Department of Histology, Cytology, and Embryology, Institute of Medicine, I. S. Turgenev Orel State University, Orel, Russia. gennadii.piavchenko@yandex.ru., Dutta P; Department of Histology, Cytology, and Embryology, Institute of Medicine, I. S. Turgenev Orel State University, Orel, Russia., Novikova NS; Department of General Pathology and Pathophysiology, Institute of Experimental Medicine, St. Petersburg, Russia., Pugach VA; Department of General Pathology and Pathophysiology, Institute of Experimental Medicine, St. Petersburg, Russia., Korneva EA; Department of General Pathology and Pathophysiology, Institute of Experimental Medicine, St. Petersburg, Russia., Nozdrin VI; Center for Preclinical Research, Retinoids Company, Moscow, Russia.; Department of Histology, Cytology, and Embryology, Institute of Medicine, I. S. Turgenev Orel State University, Orel, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2017 Sep; Vol. 163 (5), pp. 677-680. Date of Electronic Publication: 2017 Sep 25.
DOI: 10.1007/s10517-017-3877-9
Abstrakt: Local application of the Dorogov's antiseptic-stimulant onto the skin of 2-month-old male Sprague-Dawley rats in a low dose (0.5 g/kg/day) for 1 week increased motor and ultrasonic activity of experimental animals and the content of activated c-Fos + neurons on the cingular, motor, insular, and pyriform cortex and in the striatum.
Databáze: MEDLINE
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