Improved Calcium Scoring at Dual-Energy Computed Tomography Angiography Using a High-Z Contrast Element and Novel Material Separation Technique.
| Autor: | Lambert JW; From the University of California, San Francisco, San Francisco, CA., Sun Y, Ordovas KG, Gould RG, Wang S, Yeh BM |
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| Jazyk: | angličtina |
| Zdroj: | Journal of computer assisted tomography [J Comput Assist Tomogr] 2018 May/Jun; Vol. 42 (3), pp. 459-466. |
| DOI: | 10.1097/RCT.0000000000000676 |
| Abstrakt: | Objectives: The aim of this study was to compare the accuracy of existing dual-energy computed tomography (CT) angiography coronary artery calcium scoring methods to those obtained using an experimental tungsten-based contrast material and a recently described contrast material extraction process (CMEP). Methods: Phantom coronary arteries of varied diameters, with different densities and arcs of simulated calcified plaque, were sequentially filled with water, iodine, and tungsten contrast materials and scanned within a thorax phantom at rapid-kVp-switching dual-energy CT. Calcium and contrast density images were obtained by material decomposition (MD) and CMEP. Relative calcium scoring errors among the 4 reconstructed datasets were compared with a ground truth, 120-kVp dataset. Results: Compared with the 120-kVp dataset, tungsten CMEP showed a significantly lower mean absolute error in calcium score (6.2%, P < 0.001) than iodine CMEP, tungsten MD, and iodine MD (9.9%, 15.7%, and 40.8%, respectively). Conclusions: Novel contrast elements and material separation techniques offer improved coronary artery calcium scoring accuracy and show potential to improve the use of dual-energy CT angiography in a clinical setting. |
| Databáze: | MEDLINE |
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