Crystal structures of pure 3-(4-bromo-2-chloro-phen-yl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2- d ][1,2,4]triazin-4(3 H )-one and contaminated with 3-(4-bromo-phen-yl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2- d ][1,2,4]triazin-4(3 H )-one.

Autor: Wahedy K; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Alazhar University-Gaza, Gaza Strip, Palestinian Territories., Abu Thaher B; Faculty of Science, Chemistry Department, Islamic University of Gaza Strip, Gaza Strip, Palestinian Territories., Schollmeyer D; Department of Organic Chemistry, Johannes Gutenberg-University Mainz, Duesbergweg 10-14, 55099 Mainz, Germany., Almasri I; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Alazhar University-Gaza, Gaza Strip, Palestinian Territories., Morjan R; Faculty of Science, Chemistry Department, Islamic University of Gaza Strip, Gaza Strip, Palestinian Territories., Qeshta B; Faculty of Science, Chemistry Department, Islamic University of Gaza Strip, Gaza Strip, Palestinian Territories., Deigner HP; Hochschule Furtwangen (HFU), Fakultät Medical and Life Sciences, Jakob-Kienzle Strasse 17, 78054 Villingen-Schwenningen, Germany.; Fraunhofer IZI, EXIM Rostock, Perlickstrasse 1, 04103 Leipzig, Germany.
Jazyk: angličtina
Zdroj: Acta crystallographica. Section E, Crystallographic communications [Acta Crystallogr E Crystallogr Commun] 2017 Aug 15; Vol. 73 (Pt 9), pp. 1341-1343. Date of Electronic Publication: 2017 Aug 15 (Print Publication: 2017).
DOI: 10.1107/S2056989017011732
Abstrakt: The side product of the cyclo-condensation reaction between ethyl benzimidazole-2-carboxyl-ate and the nitrile imine of the corresponding hydrazonyl chloride, C 20 H 11 BrClN 5 O, crystallized in two crystal forms. Form ( 1 ) is a co-crystal of the target compound (without any chlorine substituent) and a side product containing a Cl atom in position 2 of the bromo-phenyl group, C 20 H 12 BrN 5 O·0.143C 20 H 11 BrClN 5 O. ( 2 ) contains the pure side product. The slightly different conformation of the ring systems leads to a different packing of ( 1 ) and ( 2 ), but both crystal structures are dominated by π-π inter-actions.
Databáze: MEDLINE
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