A Reassessment of the Marrubium Vulgare L. Herb's Potential Role in Diabetes Mellitus Type 2: First Results Guide the Investigation toward New Horizons.
| Autor: | Rodríguez Villanueva J; Biomedical Sciences Department, Pharmacy and Pharmaceutical Technology Unit, Faculty of Pharmacy, University of Alcalá, Ctra. de Madrid-Barcelona (Autovía A2) Km. 33,600, 28805 Alcalá de Henares, Madrid, Spain. therealworldvsme@hotmail.com., Martín Esteban J; Phytotherapy Faculty, University of Barcelona, Gran Via de les Corts Catalanes, 585, 08007 Barcelona, Spain. jorgemartinesteban@gmail.com., Rodríguez Villanueva L; Faculty of Pharmacy, University of Alcalá, Ctra. de Madrid-Barcelona (Autovía A2) Km. 33,600 28805 Alcalá de Henares, Madrid, Spain. lau95.rv@gmail.com. |
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| Jazyk: | angličtina |
| Zdroj: | Medicines (Basel, Switzerland) [Medicines (Basel)] 2017 Aug 02; Vol. 4 (3). Date of Electronic Publication: 2017 Aug 02. |
| DOI: | 10.3390/medicines4030057 |
| Abstrakt: | Despite the wide variety of pharmacological activities described for the Marrubium vulgare L. herb, amazingly, only one clinical trial can be found in scientific literature. It was designed for the evaluation of its antidiabetic activity. Worse, the outcomes of this trial were contradictory to what previous in vivo mice assays had concluded. Therefore, should Marrubium vulgare be ruled out due to its lack of therapeutic potential in diabetes? The authors suggest a reevaluation of the clinical trial methodology to establish valid and final results. |
| Databáze: | MEDLINE |
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