New Advances and Challenges of Targeting Cancer Stem Cells.

Autor:	Dashzeveg NK; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Taftaf R; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Ramos EK; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Torre-Healy L; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Chumakova A; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Silver DJ; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Alban TJ; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Sinyuk M; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Thiagarajan PS; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Jarrar AM; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Turaga SM; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Saygin C; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Mulkearns-Hubert E; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Hitomi M; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio., Rich JN; Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio.; The Case Comprehensive Cancer Center, Cleveland, Ohio.; The National Center for Regenerative Medicine, Cleveland, Ohio., Gerson SL; The Case Comprehensive Cancer Center, Cleveland, Ohio.; The National Center for Regenerative Medicine, Cleveland, Ohio.; The University Hospitals Cleveland Medical Center, Cleveland, Ohio., Lathia JD; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio.; The Case Comprehensive Cancer Center, Cleveland, Ohio.; The National Center for Regenerative Medicine, Cleveland, Ohio., Liu H; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. huiping.liu@northwestern.edu.; The Case Comprehensive Cancer Center, Cleveland, Ohio.; The National Center for Regenerative Medicine, Cleveland, Ohio.; Department of Medicine (Hematology and Oncology Division) and Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.; Deparmtent of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Jazyk:	angličtina
Zdroj:	Cancer research [Cancer Res] 2017 Oct 01; Vol. 77 (19), pp. 5222-5227. Date of Electronic Publication: 2017 Sep 19.
DOI:	10.1158/0008-5472.CAN-17-0054
Abstrakt:	The second International Cancer Stem Cell Conference in Cleveland, Ohio, on September 20-23, 2016, convened 330 attendees from academic, industrial, and clinical organizations. It featured a debate on the concepts and challenges of the cancer stem cells (CSC) as well as CSC-centered scientific sessions on clinical trials, genetics and epigenetics, tumor microenvironment, immune suppression, metastasis, therapeutic resistance, and emerging novel concepts. The conference hosted 35 renowned speakers, 100 posters, 20 short talks, and a preconference workshop. The reported advances of CSC research and therapies fostered new collaborations across national and international borders, and inspired the next generation's young scientists. Cancer Res; 77(19); 5222-7. ©2017 AACR . (©2017 American Association for Cancer Research.)
Databáze:	MEDLINE
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