Vitamin D status in internationally adopted children: the northwest Italy experience.

Autor:	Raffaldi I; Department of Pediatrics, Regina Margherita Children's Hospital, University of Turin, Turin, Italy - ire_raffaldi@yahoo.it., Garazzino S; Department of Pediatrics, Regina Margherita Children's Hospital, University of Turin, Turin, Italy., Ballardini G; Unit of Pediatrics, Castelli Hospital, Verbania, Italy., Zaffaroni M; Pediatric Clinic, University of Eastern Piedmont, Novara, Italy., Grasso N; Pediatric Clinic, University of Eastern Piedmont, Novara, Italy., Bona G; Pediatric Clinic, University of Eastern Piedmont, Novara, Italy., Tovo PA; Department of Pediatrics, Regina Margherita Children's Hospital, University of Turin, Turin, Italy., Guala A; Unit of Pediatrics, Castelli Hospital, Verbania, Italy.
Jazyk:	angličtina
Zdroj:	Minerva pediatrics [Minerva Pediatr (Torino)] 2023 Apr; Vol. 75 (2), pp. 197-200. Date of Electronic Publication: 2017 Sep 15.
DOI:	10.23736/S2724-5276.17.04883-6
Abstrakt:	Background: The majority of internationally adopted children, before adoption, might have experienced malnutrition, exposure to infectious diseases, environmental deprivation, and neglect; they could also develop medical problems such as vitamin D deficiency. Scantly data are available about vitamin D status in internationally adopted children and, to our knowledge, no report exists on Italian adoptees. Methods: We carried out a prospective multicenter study, involving three Pediatric Centers in Piedmont, Italy, to collect information about 25-hydroxyvitamin D (25[OH]D) profile in adoptees, shortly after their arrival in Italy. Results: In 142/158 internationally adopted children 25(OH)D was measured: 75 males and 67 females, with a mean age of 4.22±2.2 years. Fifty-three (37.3%) of them came from Asia, 48 (33.8%) from Africa, 24 (16.9%) from Eastern Europe, and 17 (12%) from Latin America. The median level of 25(OH)D in serum was 21.5 ng/mL (IQR range 14.3-29.7 ng/mL): 26 (18.2%) of the examined children had an insufficiency of 25-OHD, whereas 36 (25.2%) had a deficiency. Adoptees with longer time of institution stay had a significant risk to develop 25(OH)D deficiency. The Asian origin proved to be a risk factor to develop 25(OH)D deficiency, whereas the age >1 year was significantly associated with 25(OH)D insufficiency. Conclusions: Our survey showed that vitamin D deficiency and insufficiency, in internationally adoptees, are frequent and relevant health problems.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu