A Newly Developed mm-Wave Sensor for Detecting Plaques of Arterial Vessels.

Autor:	Vogt S; Department of Heart Surgery, Philipps University, Marburg, Germany.; Biochemical Pharmacological Center, Cardiovascular Res Lab, Philipps University, Marburg, Germany., Detert M; Fakultät für Elektrotechnik und Informationstechnik, Otto-von-Guericke-Universität Magdeburg, Insititut für Mikro- und Sensorsysteme, Magdeburg, Germany., Wagner D; Fakultät für Elektrotechnik und Informationstechnik, Otto-von-Guericke-Universität Magdeburg, Insititut für Mikro- und Sensorsysteme, Magdeburg, Germany., Wessel J; Leibniz-Institut für innovative Mikroelektronik, IHP GmbH, Frankfurt (O), Germany., Ramzan R; Department of Heart Surgery, Philipps University, Marburg, Germany., Nimphius W; Institut für Pathologie, Philipps-Universität Marburg, Marburg, Germany., Ramaswamy A; Institut für Pathologie, Philipps-Universität Marburg, Marburg, Germany., Guha S; Leibniz-Institut für innovative Mikroelektronik, IHP GmbH, Frankfurt (O), Germany., Wenger C; Leibniz-Institut für innovative Mikroelektronik, IHP GmbH, Frankfurt (O), Germany., Jamal FI; Leibniz-Institut für innovative Mikroelektronik, IHP GmbH, Frankfurt (O), Germany., Eissa MH; Leibniz-Institut für innovative Mikroelektronik, IHP GmbH, Frankfurt (O), Germany., Schumann U; Fakultät für Elektrotechnik und Informationstechnik, Otto-von-Guericke-Universität Magdeburg, Insititut für Mikro- und Sensorsysteme, Magdeburg, Germany., Schmidt B; Fakultät für Elektrotechnik und Informationstechnik, Otto-von-Guericke-Universität Magdeburg, Insititut für Mikro- und Sensorsysteme, Magdeburg, Germany., Rose G; Fakultät für Elektrotechnik und Informationstechnik, Otto-von-Guericke-Universität Magdeburg, Insititut für Mikro- und Sensorsysteme, Magdeburg, Germany., Dahl C; Institut für Hochfrequenzsysteme, Ruhr-Universität Bochum, Bochum, Germany., Rolfes I; Institut für Hochfrequenzsysteme, Ruhr-Universität Bochum, Bochum, Germany., Notzon G; Institut für Hochfrequenzsysteme, Ruhr-Universität Bochum, Bochum, Germany., Baer C; Institut für Hochfrequenzsysteme, Ruhr-Universität Bochum, Bochum, Germany., Musch T; Institut für Hochfrequenzsysteme, Ruhr-Universität Bochum, Bochum, Germany.
Jazyk:	angličtina
Zdroj:	The Thoracic and cardiovascular surgeon [Thorac Cardiovasc Surg] 2018 Jan; Vol. 66 (1), pp. 91-98. Date of Electronic Publication: 2017 Sep 18.
DOI:	10.1055/s-0037-1606318
Abstrakt:	Background: Microcalcifications within the fibrous cap of the arteriosclerotic plaques lead to the accrual of plaque-destabilizing mechanical stress. New techniques for plaque screening with small detectors and the ability to differentiate between the smooth and hard elements of plaque formation are necessary. Method: Vascular plaque formations are characterized as calcium phosphate containing structures organized as hydroxylapatite resembling the mineral whitlockite. In transmission and reflexion studies with a simple millimeter wave (mm-wave)-demonstrator, we found that there is a narrow window for plaque detection in arterial vessels because of the tissue water content, the differentiation to fatty tissue, and the dielectric property of air or water, respectively. Result: The new sensor is based on a sensing oscillator working around 27 GHz. The open-stub capacitance determines the operating frequency of the sensor oscillator. The capacitance depends on the dielectric properties of the surrounding material. The sensor components were completely built up in surface mount technique. Conclusion: Completed with a catheter, the sensor based on microwave technology appears as a robust tool ready for further clinical use. Competing Interests: Conflict of Interest: None declared. (Georg Thieme Verlag KG Stuttgart · New York.)
Databáze:	MEDLINE
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