Poor outcomes among elderly patients hospitalized for influenza-like illness.

Autor:	Tanriover MD; a Hacettepe University Faculty of Medicine , Department of Internal Medicine , Ankara , Turkey., Bagci Bosi T; b Hacettepe University Faculty of Medicine , Department of Public Health , Ankara , Turkey., Ozisik L; a Hacettepe University Faculty of Medicine , Department of Internal Medicine , Ankara , Turkey., Bilgin E; a Hacettepe University Faculty of Medicine , Department of Internal Medicine , Ankara , Turkey., Güzel Tunçcan Ö; c Gazi University Faculty of Medicine , Department of Infectious Diseases , Ankara , Turkey., Özgen Ö; c Gazi University Faculty of Medicine , Department of Infectious Diseases , Ankara , Turkey., Tülek N; d Ankara Training and Research Hospital , Clinic of Infectious Diseases and Clinical Microbiology , Ankara , Turkey., Özsoy M; d Ankara Training and Research Hospital , Clinic of Infectious Diseases and Clinical Microbiology , Ankara , Turkey., Tezer H; e Gazi University Faculty of Medicine , Department of Pediatrics , Ankara , Turkey., Bedir Demirdağ T; e Gazi University Faculty of Medicine , Department of Pediatrics , Ankara , Turkey., Kara A; f Hacettepe University Faculty of Medicine , Department of Pediatrics , Ankara , Turkey., Basaranoglu ST; f Hacettepe University Faculty of Medicine , Department of Pediatrics , Ankara , Turkey., Aykac K; f Hacettepe University Faculty of Medicine , Department of Pediatrics , Ankara , Turkey., Ozkaya-Parlakay A; g Ankara Hematology Oncology Children's Training and Research Hospital , Pediatric Infectious Disease Department , Ankara , Turkey., Gulhan B; g Ankara Hematology Oncology Children's Training and Research Hospital , Pediatric Infectious Disease Department , Ankara , Turkey., Unal S; h Hacettepe University Faculty of Medicine , Department of Infectious Diseases and Clinical Microbiology , Ankara , Turkey.
Jazyk:	angličtina
Zdroj:	Current medical research and opinion [Curr Med Res Opin] 2018 Jul; Vol. 34 (7), pp. 1201-1207. Date of Electronic Publication: 2017 Oct 16.
DOI:	10.1080/03007995.2017.1381078
Abstrakt:	Background and Objective: Global Influenza Hospital Surveillance Network is a worldwide initiative that aims to document the burden of influenza infections among acute admissions and vaccine effectiveness in particular countries. As a partner of this platform, we aimed to determine the frequency of influenza infections among acute admissions with influenza-like illness and the outcomes of enrolled patients during the 2015-2016 influenza season in selected hospitals in Turkey. Patients and Methods: The investigators screened the hospital admission registries, chart review or available records, and screened all patients hospitalized in the previous 24-48 hours or overnight in the predefined wards or emergency room. A total of 1351 patients were screened for enrollment in five tertiary care referral hospitals in Ankara and 774 patients (57.3% of the initial screened population) were eligible for swabbing. All of the eligible patients who consented were swabbed and tested for influenza with real-time polymerase chain reaction (PCR) based methods. Results: Overall, influenza positivity was detected in 142 patients (18.4%). The predominant influenza strain was A H1N1pdm09. Outcomes were worse among elderly patients, regardless of the presence of the influenza virus. Half of the patients over 65 years of age were admitted to the intensive care unit, while one third required any mode of mechanical ventilation and one fourth died in the hospital in that particular episode. Conclusion: These findings can guide hospitals to plan and prepare for the influenza season. Effective influenza vaccination strategies, particularly aimed at the elderly and adults with chronic diseases, can provide an opportunity for prevention of deaths due to influenza-like illness.
Databáze:	MEDLINE
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