Sleep Duration and Quality as Related to Left Ventricular Structure and Function.

Autor:	Lee JH; From the Department of Psychiatry (J.-H. Lee), Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea; Department of Psychiatry (J.-H. Lee, Mansur, McIntyre), University of Toronto, Ontario, Canada; Department of Psychiatry (J.-H. Lee), Kosleep Center, Seoul, Korea; Center for Cohort Studies (Park), Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, Korea; Departments of Preventive Medicine (Ryoo, Oh, Jung), School of Medicine, Kyung Hee University, Seoul, Korea; Total Healthcare Center (Kang, Jung), Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, Korea; Mood Disorders and Psychopharmacology Unit (Mansur, Y. Lee, McIntyre), University Health Network, Toronto, Ontario, Canada; Interdisciplinary Laboratory of Clinical Neurosciences (LINC) (Mansur), Department of Psychiatry, Universidade Federal de São Paulo (UNIFESP), Brazil; Department of Medicine (Alfonsi), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Institute of Medical Science (Y. Lee), University of Tornoto, Ontario, Canada; Clinical Research Coordination Center (Shin), Office of Public Relations and Collaboration, National Cancer Center, Goyang, Korea; and Department of Pharmacology (McIntyre), University of Toronto, Ontario, Canada., Park SK, Ryoo JH, Oh CM, Kang JG, Mansur RB, Alfonsi JE, Lee Y, Shin SH, McIntyre RS, Jung JY
Jazyk:	angličtina
Zdroj:	Psychosomatic medicine [Psychosom Med] 2018 Jan; Vol. 80 (1), pp. 78-86.
DOI:	10.1097/PSY.0000000000000528
Abstrakt:	Objective: Inadequate sleep is associated with increased risk of cardiovascular events; however, the associations between sleep duration or quality and cardiac function or structure are not well understood. This cross-sectional study was conducted to investigate to what extent sleep duration and quality are associated with left ventricular (LV) diastolic dysfunction or structural deterioration. Methods: A total of 31,598 healthy Korean adults who received echocardiography and completed the Pittsburg Sleep Quality Index were enrolled in this study. Participants were stratified into three groups by self-reported sleep duration (i.e., <7, 7-9, >9 hours) and into two groups by subjective sleep quality. Sleep duration was also assessed as a continuous variable. The odds ratios for impaired LV diastolic function, increased relative wall thickness, and LV hypertrophy (LVH) were compared between groups using multivariable logistic regression analyses. Results: After adjustment for confounding variables (e.g., age, smoking, body mass index), there was a statistically significant association between short sleep duration (<7 hours) and greater LVH (fully adjusted odds ratio = 1.32 [95% confidence interval {CI} = 1.02-1.73]). Short sleep duration was also significantly associated with greater LVH (0.87 per hour [95% CI = 0.78-0.98]) and increased relative wall thickness (0.92 [95% CI = 0.86-0.99]), but there was no significant association between sleep and LV diastolic function. Among individuals with normal sleep duration, poor quality of sleep was not associated with adverse cardiac measures. Conclusions: These results indicate that short sleep duration (<7 hours) is associated with unfavorable LV structural characteristics. The association of insufficient sleep with adverse cardiovascular health outcomes may be mediated in part by adverse changes in cardiac structure and function.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu