Epidemiological and molecular analysis of hepatitis B virus infection in manicurists in Central Brazil.

Autor: Cavaretto L; Universidade Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil., Motta-Castro ARC; Universidade Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.; Fundação Oswaldo Cruz, Campo Grande, Mato Grosso do Sul, Brazil., Teles SA; Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Souza FQ; Universidade Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil., Cardoso WM; Universidade Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil., de Rezende GR; Universidade Federal da Grande Dourados, Campo Grande, Mato Grosso do Sul, Brazil., Tanaka TSO; Universidade Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil., Bandeira LM; Universidade Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil., Cesar GA; Universidade Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil., Puga MAM; Universidade Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil., Nepomuceno BB; Universidade Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil., Lago BV; Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.; Instituto de Tecnologia em Imunobiológicos-Biomanguinhos, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil., Fernandes-Fitts SM; Universidade Federal do Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Jazyk: angličtina
Zdroj: Journal of medical virology [J Med Virol] 2018 Feb; Vol. 90 (2), pp. 277-281. Date of Electronic Publication: 2017 Sep 25.
DOI: 10.1002/jmv.24940
Abstrakt: The aim of this study was to investigate the serological and molecular prevalence of hepatitis B virus (HBV) infection in 514 manicurists/pedicurists and identify the risk factors related with this infection. Samples were tested for HBV serological markers, hepatitis C virus (HCV), and human immunodeficiency virus (HIV) by enzyme-linked immunosorbent assay (ELISA). Anti-HBc-positive samples were tested to investigate occult hepatitis B by PCR. HBsAg-positive samples were genotyped and the viral loads of HBV-DNA positive samples were quantified. The overall HBV prevalence was 5.6% (29/514) and of HBsAg was 0.4% (2/514). One case of occult hepatitis B was found. The genotypes A1 and F2 were identified in two HBsAg-positive samples. Low level of education, not being born in the State of Mato Grosso do Sul and working in the central region of the city were associated with the HBV infection. No single manicurist/pedicurist was infected by HCV or HIV. These findings suggest that despite the exposure to blood contact, this occupation was not associated to an increased risk of acquiring HBV, HCV, and HIV infections.
(© 2017 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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