Intraoral stents in preventing adverse radiotherapeutic effects in lip cancer patients.

Autor:	Rocha BA; Oncologic Dentistry Service, Santa Casa Hospital, Montes Claros, Praça Honorato Alves, 22 - Centro, Montes Claros, Minas Gerais 39400-103, Brazil., Lima LMC; Radiotherapy Service, Santa Casa of Montes Claros, Praça Honorato Alves, 22 - Centro, Montes Claros, Minas Gerais 39400-103, Brazil., Paranaíba LMR; Dental School, University of Montes Claros, Av Rui Braga - Vila Mauricéia - Campus Darcy Ribeiro, Montes Claros, Minas Gerais 39401-089, Brazil.; Health Science Program, State University of Montes Claros, Montes Claros, Av. Cula Mangabeira, 562, Montes Claros, Minas Gerais 39401-001, Brazil., Martinez ADS; Radiotherapy Service, Santa Casa of Montes Claros, Praça Honorato Alves, 22 - Centro, Montes Claros, Minas Gerais 39400-103, Brazil., Pires MBO; Oncologic Dentistry Service, Santa Casa Hospital, Montes Claros, Praça Honorato Alves, 22 - Centro, Montes Claros, Minas Gerais 39400-103, Brazil.; Dental School, University of Montes Claros, Av Rui Braga - Vila Mauricéia - Campus Darcy Ribeiro, Montes Claros, Minas Gerais 39401-089, Brazil., de Freitas EM; Oncologic Dentistry Service, Santa Casa Hospital, Montes Claros, Praça Honorato Alves, 22 - Centro, Montes Claros, Minas Gerais 39400-103, Brazil.; Health Science Program, State University of Montes Claros, Montes Claros, Av. Cula Mangabeira, 562, Montes Claros, Minas Gerais 39401-001, Brazil., Vilas Boas CV; Oncologic Dentistry Service, Santa Casa Hospital, Montes Claros, Praça Honorato Alves, 22 - Centro, Montes Claros, Minas Gerais 39400-103, Brazil., de Melo Filho MR; Oncologic Dentistry Service, Santa Casa Hospital, Montes Claros, Praça Honorato Alves, 22 - Centro, Montes Claros, Minas Gerais 39400-103, Brazil.; Dental School, University of Montes Claros, Av Rui Braga - Vila Mauricéia - Campus Darcy Ribeiro, Montes Claros, Minas Gerais 39401-089, Brazil.
Jazyk:	angličtina
Zdroj:	Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology [Rep Pract Oncol Radiother] 2017 Nov-Dec; Vol. 22 (6), pp. 450-454. Date of Electronic Publication: 2017 Sep 01.
DOI:	10.1016/j.rpor.2017.08.003
Abstrakt:	Aim: To fabricate and evaluate the efficacy of individualized intraoral stents to minimize the potential side effects of radiation on oral tissues in patients with early stages of lip cancer. Background: Lower lip cancer is a common tumor found almost exclusively in middle-aged and elderly males. Surgery is the most common treatment of choice, although for less extensive lesions, exclusive radiotherapy may be preferred. Some studies have found that the use of intraoral stents in patients with intraoral cancer (e.g., of the tongue or floor of the mouth) obtained favorable results in preventing unnecessary radiation doses to adjacent normal tissue and reducing oral complications. However, studies investigating the efficacy of individualized intraoral stents in patients with lip cancer have not been reported in the literature. Materials and Methods: Six patients with early stage lip cancer were eligible for curative radiotherapy and personalized intraoral stents. The stents were fabricated and all participants were evaluated for the occurrence of oral complications. Results: The regions of the oral mucosa protected from radiation by intraoral stents showed no mucositis. One patient complained of mild oral dryness but without interference in habits. At follow-up, none of the patients had late xerostomia or signs of dental caries by radiation. Conclusions: The use of individualized intraoral stents was shown to be promising in reducing the adverse effects of radiation therapy in lip cancer patients. These findings highlight the importance of a multidisciplinary team during oncological therapy.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu