| Autor: |
Reid K, Surridge DH, Morales A, Condra M, Harris C, Owen J, Fenemore J |
| Jazyk: |
angličtina |
| Zdroj: |
Lancet (London, England) [Lancet] 1987 Aug 22; Vol. 2 (8556), pp. 421-3. |
| DOI: |
10.1016/s0140-6736(87)90958-5 |
| Abstrakt: |
48 subjects meeting strict diagnostic criteria for psychogenic impotence took part in a 10 week placebo-controlled, double-blind, partial crossover trial of yohimbine (18 mg a day) for restoring erectile function. At the end of the first arm of the trial 62% of the yohimbine group and 16% of the placebo group reported some improvement in sexual function (chi 2 = 10.41, df = 2, p less than 0.05). 21% of the originally placebo-treated group noticed some improvement over pre-treatment levels when they were put on yohimbine in the second arm of the trial. Overall 46% of those who received yohimbine reported a positive response to the drug, a response rate very similar to that observed in a previous study of patients with organic impotence. Response to yohimbine thus seems to be unrelated to current groupings of the cause of impotence. Yohimbine is a safe treatment for psychogenic impotence that seems to be as effective as sex and marital therapy for restoring satisfactory sexual functioning. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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