Multi-level obstruction in obstructive sleep apnoea: prevalence, severity and predictive factors.

Autor: Phua CQ; Department of Otorhinolaryngology,Khoo Teck Puat Hospital,Singapore., Yeo WX; Department of Otorhinolaryngology,Khoo Teck Puat Hospital,Singapore., Su C; Division of Biostatistics,Clinical Research Unit,Khoo Teck Puat Hospital,Singapore., Mok PKH; Department of Otorhinolaryngology,Khoo Teck Puat Hospital,Singapore.
Jazyk: angličtina
Zdroj: The Journal of laryngology and otology [J Laryngol Otol] 2017 Nov; Vol. 131 (11), pp. 982-986. Date of Electronic Publication: 2017 Sep 05.
DOI: 10.1017/S0022215117001906
Abstrakt: Objectives: To characterise multi-level obstruction in terms of prevalence, obstructive sleep apnoea severity and predictive factors, and to collect epidemiological data on upper airway morphology in obstructive sleep apnoea patients.
Methods: Retrospective review of 250 obstructive sleep apnoea patients.
Results: On clinical examination, 171 patients (68.4 per cent) had multi-level obstruction, 49 (19.6 per cent) had single-level obstruction and 30 (12 per cent) showed no obstruction. Within each category of obstructive sleep apnoea severity, multi-level obstruction was more prevalent. Multi-level obstruction was associated with severe obstructive sleep apnoea (more than 30 events per hour) (p = 0.001). Obstructive sleep apnoea severity increased with the number of obstruction sites (correlation coefficient = 0.303, p < 0.001). Multi-level obstruction was more likely in younger (p = 0.042), male (p = 0.045) patients, with high body mass index (more than 30 kg/m2) (p < 0.001). Palatal (p = 0.004), tongue (p = 0.026) and lateral pharyngeal wall obstructions (p = 0.006) were associated with severe obstructive sleep apnoea.
Conclusion: Multi-level obstruction is more prevalent in obstructive sleep apnoea and is associated with increased severity. Obstruction at certain anatomical levels contributes more towards obstructive sleep apnoea severity.
Databáze: MEDLINE
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