Stroke and temporal arteritis: A study of 6 cases.

Autor:	Lago A; Servicio de Neurología, Hospital Universitario La Fe, Valencia, España. Electronic address: aida.lago@sen.es., Tembl JI; Servicio de Neurología, Hospital Universitario La Fe, Valencia, España., Fortea G; Servicio de Neurología, Hospital Universitario La Fe, Valencia, España., Morales L; Servicio de Neurología, Hospital Universitario La Fe, Valencia, España., Nieves C; Servicio de Neurología, Hospital Universitario La Fe, Valencia, España., Campins M; Servicio de Neurología, Hospital Universitario La Fe, Valencia, España., Aparici F; Servicio de Radiología, Hospital Universitario La Fe, Valencia, España.
Jazyk:	English; Spanish; Castilian
Zdroj:	Neurologia (Barcelona, Spain) [Neurologia (Engl Ed)] 2020 Mar; Vol. 35 (2), pp. 75-81. Date of Electronic Publication: 2017 Aug 30.
DOI:	10.1016/j.nrl.2017.06.003
Abstrakt:	Introduction: Though uncommon, ischaemic stroke due to temporal arteritis carries serious difficulties for diagnosis and subsequent management and requires a high level of suspicion. Methods: We analysed a series of 6 patients with biopsy-proven temporal arteritis presenting with ischaemic stroke. We discuss clinical characteristics, difficulties of assessment, short- and long-term progression, treatment, and the usefulness of new diagnostic techniques. Results: Our sample of 6 patients had a mean age of 68.3 years; 50% were women. The majority of patients showed systemic symptoms. Anterior and posterior circulation were affected similarly. MRI angiography, Doppler sonography, and PET-CT proved to be very useful for diagnosis and treatment. Mean follow-up time was 26 months. Clinical outcomes were far from good: 33% scored≥3 on the modified Rankin scale, including one death. Two patients had recurrent stroke despite treatment with full doses of corticosteroids, and 2 underwent angioplasty. Conclusions: Stroke caused by giant cell arteritis is a serious and potentially severe condition which requires a high level of suspicion and early treatment with corticosteroids. New diagnostic techniques contribute to refining patient assessment and identifying the optimal treatment. Endovascular treatment may be a valid therapeutic option in selected patients. (Copyright © 2017 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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