| Autor: |
Liu S; 1 School of Medicine, Shandong University, Jinan, Shandong Province, China.; 2 Department of Radiology, Taian City Central Hospital, Taian, Shandong Province, China., Li M; 1 School of Medicine, Shandong University, Jinan, Shandong Province, China.; 2 Department of Radiology, Taian City Central Hospital, Taian, Shandong Province, China., Tang W; 3 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China., Wang G; 1 School of Medicine, Shandong University, Jinan, Shandong Province, China., Lv Y; 2 Department of Radiology, Taian City Central Hospital, Taian, Shandong Province, China. |
| Abstrakt: |
Objective Functional magnetic resonance imaging (fMRI) analysis of the effects of acupuncturing the Tongli (HT 5 ) and Tongli (HT 5 )-Xuanzhong (GB 39 ) acupoints on the normal language areas with a view to providing a theoretical basis for using acupuncture to treat patients with aphasia. Methods This study enrolled healthy volunteers. The following acupoints were stimulated: right Tongli (HT 5 ), right Tongli (HT 5 )-Xuanzhong (GB 39 ), right Tongli (HT 5 ) sham acupuncture, left Tongli (HT 5 ), and left Tongli (HT 5 )-Xuanzhong (GB 39 ) acupoints. Acupuncture stimulation was delivered whilst fMRI scanning of the brain was undertaken. Results Ten healthy volunteers (five males) were included in this study (mean age 44.5 ± 2.5 years; range 40-55 years). Based on the statistical analyses, only acupuncturing the right Tongli (HT 5 ) acupoint resulted in activation of multiple regions of the bilateral cerebral hemisphere that were closely related to the language regions. The right Tongli (HT 5 ) stimulation had a laterality index of 0.0952; with the activated voxels on the left side language-related areas being greater than those on the right side. Conclusions Acupuncturing the right Tongli (HT 5 ) acupoint results in activation of the bilateral language-related areas, so this acupoint might be useful for the acupuncture treatment of aphasia caused by cerebral infarction. |
